substance use disorder specifier criteria - ans ---Mild: 2-3 symptoms
Moderate: 4-5 symtpoms
Severe: >6 symptoms
DSM for substance use disorder - ans ---over 12 months
use increase amount
persistant desire or can't cut down
lots of time spent on substance
craving
failure to fill roles
social/personal problems
activities given up/reduced
use when physically hazardous
continue despite problem
tolerence
withdrawal
abuse - ans ---use of any drug in a manner that deviates from approved social or medial patterns
vvvvvvvvvvv cross tolerence - ans ---the ability of one drug to be substituted for another each usually producing the same effects ex: diazepam and barbituates
misuse - ans ---similar to abuse, but usually applies to drugs prescribed by physicians that are not used
properly
tolerence - ans ---after repeated administration, a given dose of a drug produces a decreased effect or larger doses must be administered to obtain the effect observed with the original dose
withdrawal - ans ---a substance specific syndrome that occurs after stopping or reducing the amount of drug or substance that has been used regularly over a prolonged period
acamprosate; what, side effects, dose - ans ---what: alcohol relapse prevention; "artificial alcohol" decreases glutamate and increases GABA
side effects: anxiety, depression, diarrhea, decreased libido, flu like
dose: 666mg TID
must be abstinent from etoh first
buprenorphine; moa, who can use - ans ---MOA: partial opioid agonist, prevents pleasurable effects, is
a opiate analgesic
who: pregnant okay, must be in mild withdrawal to start
buprenorphine dosing - ans ---must be in withdrawal to start
SL 8-32mg/d
which medications are in Suboxone - ans ---buprenorphine and naloxone
buproprion; dosing - ans ---for smoking cessation: begin 7-14d before stop date; 150mg SR in am x6 days then increase to 150mg SR BID tx for 7-9 weeks
vvvvvvvvvvv