Advanced Pharmacology-NR 508 Questions and Answers Already Passed

Advanced Pharmacology-NR 508 Questions and Answers Already Passed State the three (3) most important characteristics of any drug. effectiveness, safety, selectivity Is it possible to have a selective drug? No, all medications have side effects Define the four phases of pharmacokenetics. Absorption, distribution, metabolism and excretion Define pharmacodynamics. The nature and intensity of the response the drug has on the body Name the three most important goals of pre-administration assessment. Evaluate effects, identify high risk patients, and assess for self care What factors can predispose an individual to adverse reactions from drugs? Allergies, pregnancy, age, genetics and pathological disease (kidney or liver) What measures help reduce adverse reactions of medication administration? A thorough patient history to identify those who might be high risk and education What type of research is required to assess drug therapies? A randomized control trial is required for all new medications What is a "blinded" study? Participants don't know if they belong to the control or experimental group Which Amendment strengthened drug regulation after the Thalidomide tragedy in Europe? Harris-Kefauver Amendment to the FDA and the Cosmetic act of 1962 What is the purpose of having a trade name (proprietary or brand name) for a drug? Trade names are easy to recall and pronounce, and good for marketing purposes What is one of the problems with trade names? Using two brand name drugs that have the same ingredient can lead to overdose Binds and blocks peptidases? Penicillin's commonly used to treat urinary tract infections? Floroquinolones inhibits cell wall synthesis Cephalosporins prevents translocation Macrolides Beta Lactam ring Penicillin inhibits folic acid synthesis Sulfonomides Has a disulfiram like reaction when taken with alcohol Cephalosporins Gram positive Macrolides causes prolonged QT interval Flouroquinolones Causes GI upset, hepatotoxicity, flatulence, jaundice,