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Samenvatting Vierde en laatste hoofdstuk van Hematologie van Anneleen Cottyn

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2021/2022 Written for academic year
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Hogeschool West-Vlaanderen (HoWest)
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MLT03 - Werken In Een Hemato-klinisch Lab (MLT03)
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Alles over de hemostase, proces waarbij een bloeding stopt. Hierbij zijn ook de schema's die in de les moeten worden voorbereid aanwezig met bijhorende laboratoriumdiagnostiek en ziektebeelden

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4 Hemostase
= proces dat er voor zorgt dat de bloeding wordt gestelpt bij bescahdiging van bloedvat
Vasocontrictie
= Vernauwen bloedvatwand → verminderde bloedtoevoer → minder bloeddoorstroming
→ makkelijker voor bloedplaatjes om te aggregeren
Primaire hemostase
= Adhesie + aggregatie van bloedplaatjes aan beschadigde vaatwand
Collageen en Von Willebrand factor belangrijk
4.2.1 Verschillende stappen




1. Adhesie: bloedplaatjes hechten
zich vast aan collageenvezels via
VwF
2. Activatie bloedplaatjes door
collageen → trombocyt verandert
van vorm
3. Secretie: trombocyt geeft ADP
(adenosinedifosfaat) en
tromboxaan A2 af = activatoren
om andere trombocyten te
activeren (B)
4. Aggregatie: geactiveerde
trombocyten hechten aan
geadhereerde trombocyten (C)
Connected book
image
E. Ten Boekel, B.A. de Boer Heron-reeks - Klinische chemie en hematologie voor analisten 1
Edition: Unknown ISBN: 9789491764516 Edition: 3

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