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Chapter 10 - HIV & AIDS - HIV/AIDS lecture notes

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 Acquired Immunodeficiency Syndrome (AIDS) o Syndrome caused by a viral disease o HIV  Depletes the body’s Th cells o Incidence  WW 5 million/year  US ~31,000 cases/year  HIV o HIV-1  Cause of HIV in Western Hemisphere and Europe o HIV-2  Cause of HIV in Africa and Southeast Asia  Uncommon o Subtypes  3 Major M (main), N (new) and O (outlier)  Based on nucleotide sequence analyses of the env and gag genes there are at least 10 subtypes (A-J)  Possible combinations  Possible preferred transmission route based upon subtype

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