SBB Review Questions with 100% Correct Answers

Band 3 Correct Answer macrocomplex of proteins including: -Rh -RhAG -LW (ICAM-4) -GPA -GPB -CD47 ATP source for RBCs Correct Answer 90% from Glycolysis (Embden-Meyerhoff pathway) 10% from pentose phosphate pathway Methemoglobin Reductase Pathway Correct Answer necessary to maintain heme iron in ferrous (Fe2+) state Deficiency causes accumulation of methemoglobin, nonfunctional from of Hgb Leubering Rapaport Shunt Correct Answer permits accumulation of 2,3-DPG "Tense form" of Hgb Correct Answer DEOXYGENATED widening of beta-chain lower affinity for O2 expels 2,3-DPG "Relaxed form" of Hgb Correct Answer OXYGENATED beta-chain pulled together higher affinity for O2 expels 2,3-DPG "Shift Right" Correct Answer higher P50 value decreased pH (increased H+ ion), acidosis increased 2,3-DPG higher temperature high pCO2 Seen in compensated anemia "Shift Left" Correct Answer lower P50 value increased pH (decresed H+ ion), alkalosis decreasede 2,3-DPG lower temeratures low pCO2 Seen in storage of RBC Type 2 precursor Correct Answer Gal-GlcNAc B1-4 Type 1 precursor Correct Answer Gal-GlcNAc B1-3 Secreted (Se, Le) Type 2 H antigen transeferase & Sugar Correct Answer FUT-1 Alpha-2-L-fucosyltransferase Fuctose alpha1-2 A antigen transferase & sugar Correct Answer D-galactosaminetrasferase N-acetylgalactosamine alpha1-3 B antigen transferase & sugar Correct Answer D-galacotsyltransferase galactose alpha1-3 Ax subgroup Correct Answer weakly positive anti-A weakly positive anti-A,B Am subgroup Correct Answer Negative anti-A Secretes A & H Ael subgroup Correct Answer Negative anti-A Secretes H only Highest expression of H Lowest expression of H Correct Answer O>A2>B>A2B>A1>A1B> H deficient Lewis transferase & Sugar Correct Answer FUT-3 Fuctose alpha1-4 Type 1 H antigen transferase & sugar Correct Answer FUT-2 Fuctose alpha1-2 anti-Le bh vs anti-Le bl Correct Answer Anti-Le bh= reacts best with Leb & H are on rbc