CPJE Exam Questions With 100% Correct Answers | Verified | Updated 2024

CPJE Exam Questions With 100% Correct Answers | Verified | Updated 2024 What are Big Inducers? - answerPhenytoin Smoking Phenobarbital Oxcarbazepine Rifampin (rifabutin, rifapentine) Carbamazepine (and is an auto-inducer) St John's Wort What are b inhibitors? - answerG Pacman Grapefruit PIs (protease inhibitors) Azole antifungals Cyclosporine and cimetidine, H2RA is most diffult to use due to DIs and androgen-blocking effects (that can cause gynecomastia-swollen or painful breast tissue or impotence) Amiodarone (and dronedarone) Non-HP CCBs diltiazem and verapamil What drug interaction are we concern with for amiodarone? - answerWarfarin and digoxin. dose of digoxin and warfarin should be decreased. Drug interaction concern with digoxin? - answerDecline in renal function or hypokalemia will result in increased digoxin levels. Other drugs that may lower heart rate < 60 bpm. ie BB, non-DHP CCB, amiodarone, dexmedetomidine (precedex), cloniddine and opioids What drugs can result in additive K+ accumulation? - answerACEIs, ARBs, Aliskiren, amiloride, triamterene, eplerenone, spironolactone, salt substitutes, drospirenone oral contraceptives Bactrim, Calcineurin inhibitors, canglifozin What are side effects of Tamiflu? - answerHallucination, confusion, and strange behavior in children What is the common side effect of opioids? - answerThey can cause histamine-induced skin rash or itching. Reaction can be reduced via pre-medication with an antihistamine What drugs are commonly associated with photosensitivity? - answerSulfa Abx Tetracycline NSAIDs Amiodarone Chloroquine Coal Tar Oral and topical retinoids phenothiazines psoralens Quinidine FQ Tacrolimus Diuretics, thiazide, loops Topical 5-fu Metronidazole St John's WortPDE-5 inhibitors Cyclosporine Drugs for SJS/TEN? - answerSulfamethoxa