HNMR Spectroscopy - Organic Chemistry

-
MAGNETIC
NUCLEAR Resonance
Spectroscopy


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THE BASIS upon WHICH NMR WORKS :



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m



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man
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NMR MEASURES FREE INDUCTION decry !
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NOTE : Adjacen
M
hydrogen
BONdEd
E AE
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WCLEi ARE CLASSIFIED By Domic MASS And Acom Number .
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from EACH OTHER
Ye Have
perfectly Spierreal Spr +
&
THE NUMBEROf
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charge
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a




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REPORTE
The
w llEi are Exposed To To
,
some SPECTRUM .




from for A of presson
of the reclEi Are ExcrEd L To B STATE THES .
Spi-ferp Frequency is CALLED The in
part per Mulron (PPM) and MES CONSTAN

grew "Type"
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Resource
Frequency
. As THE NUCLEi RELAT Back To

ground
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THEY EMP Ar NMR
SIGNAL
. THE THIS CAN ALSO BE AffECTED
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decay Surround

SHIELDMY/DESHIELDMG
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g
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is .
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magnetr
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H-NMR SPECTRA
Analyzing
SITELd THE from feld WHEN
Extremely
magnetic
NoclEns The Exterior .




ACOMS ARE NEARBY THEY CAN CAUSE THE ELECTRON JENSMY SHI
ELECTRONEGAINE
, TO




Compound "H
REFERENCE is TMS SiCH3 + Effectrely deShielding The redEus .




Field Electrons of Aromate

Ring
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magnetic
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averEns




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field And Causes a
desHiElding
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MS O u r


idental
from Alkenes
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SHIELD Effects &
:
THE
Carbony


O DEPEND On THE ORIENTATION

C C
of THE
Hydrogen .
THIS Is CALLED


AlkynE
m ua
c n
n n a m
e
s o m
n oe o
enn e
Amastropy
Magnetic
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zu - - - - - -

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ALKENE
3 MOLECCAR
SHIELdEd CONNECTIMY
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Spro-Spi occurs




doe frelds of -
magnetic Merry mechei
weak
Spirss
to . M
dOESN TELL
WHAT us :




of
AdjACENTHy
drog
THES MA Ens TO SEVERAL SMALLER PEARS THE DISTANCE BETWEEN THESE SMALLER PEAks
FEATURE of SPECTRUM
g
o
.



info ABOUT Molecule
Carbonyl

(J)
He IS THE
COUPLING
CONSTANT WHA DECREASES AS BONDS
SEPARATING
THE ACOMS INCREASES .




of
Mary Types of proons
unsaturation
Number -
How

Signals
·




3
Each

cupine OFCISATURATION : rig
of PEAk of Eselt or DECREASES
Hydrogenes
How
Inegrerow Mary
·




DEGREE
Type

SHAPE of NMR PEAR #ABY2
NeigArsoveming proxons
·




DoV 20 + 2 + N H
-Shielding/deshrelding
·
Chemiere SHifT = -
X -




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# of
Horogens