Psychiatry-Pharmacology (USMLE) Exam 2024

Psychiatry-Pharmacology (USMLE) Exam 2024 Drug of choice for management of chronic generalized anxiety disorder - answerantidepressants <i>velaxafine and SSRIs preferred over TCAs What drugs can be used for acute treatment of generalized anxiety disorder or as adjuncts during initiation of antidepressant therapy? - answerbenzodiazepines Name a second-line agent for generalized anxiety disorder. - answerbuspirone <i>alternative agents: hydroxyzine and pregabalin Drug of choice for panic disorder - answerSSRIs List 2 adverse effects of alprazolam that do not make it an ideal choice for treatment of panic disorder. - answerrebound anxiety between doses withdrawal syndromes, including seizures Drug of choice for social anxiety disorder - answerSSRIs List 3/5 FDA-approved drugs for the treatment of obsessive-compulsive disorder. - answerclomipramine fluoxetine fluvoxamine paroxetine sertraline <i>benzodiazepines or antipsychotic drugs can be added for highly anxious patients Drug of choice for PTSD - answerSSRIs List 2 SSRIs approved for the <i>ACUTE</i> treatment of PTSD. Which is indicated for long-term management as well? - answersertraline: long-term management as well paroxetine Drug of choice for performance anxiety - answerpropranolol <i>and other beta-blockers What amino acid precursor gives rise to dopamine? - answertyrosine <i>must be transported across the blood-brain barrier into the dopamine neuron What transporter allows for tyrosine uptake in the presynaptic neuron? - answersystem L <i>Na+-independent manner What is the rate-limiting enzyme in dopamine synthesis? - answertyrosine hydroxylase <i>tetrahydrobiopterin cofactor required What enzyme converts DOPA to dopamine? - answerDOPA decarboxy