LANGE Q&
A™
, FOURTH EDITION
For more information about this title, click here
Contents
Contents
Preface ............................................................................................................................................................................ 5
,Questions ................................................................................................................................................................. 9
Answers and Explanations .................................................................................................................................. 23
Questions ............................................................................................................................................................... 35
Answers and Explanations .................................................................................................................................. 45
Questions ............................................................................................................................................................... 51
Answers and Explanations .................................................................................................................................. 68
Questions ............................................................................................................................................................... 79
Answers and Explanations .................................................................................................................................. 92
Questions ............................................................................................................................................................... 99
Answers and Explanations ................................................................................................................................ 112
Questions ............................................................................................................................................................. 119
Answers and Explanations ................................................................................................................................ 129
Questions ............................................................................................................................................................. 135
Answers and Explanations ................................................................................................................................ 148
Questions ............................................................................................................................................................. 157
Answers and Explanations ................................................................................................................................ 168
iii
,iv Contents
1. Muscles and Joints ..................................................................................................................................... 175
Questions ...................................................................................................................................................... 175
Answers and Explanations ........................................................................................................................ 191
2. Infection........................................................................................................................................................ 199
Questions ...................................................................................................................................................... 199
Answers and Explanations ........................................................................................................................ 217
3. Immunology and Allergy .......................................................................................................................... 229
Questions ...................................................................................................................................................... 229
Answers and Explanations ........................................................................................................................ 235
4. Diseases of the Respiratory System ........................................................................................................ 239
Questions ...................................................................................................................................................... 239
Answers and Explanations ........................................................................................................................ 252
5. Clinical Pharmacology ............................................................................................................................... 259
Questions ...................................................................................................................................................... 259
Answers and Explanations ........................................................................................................................ 267
6. Comprehensive Review ............................................................................................................................ 275
Questions ...................................................................................................................................................... 275
Answers and Explanations ........................................................................................................................ 294
References ........................................................................................................................................................... 307
Index..................................................................................................................................................................... 309
, Preface
The practice of internal medicine requires both the USMLE, making it an ideal study guide for indi-
breadth and depth of knowledge. To acquire mas- viduals preparing for licensing examinations.
tery of the subject requires extensive reading and The questions and answers reflect the increas-
clinical experience. The knowledge base is also con- ing growth of knowledge in the field of internal
stantly expanding and changing as medicine enters medicine. As a result, reviewing the answers gives
the era of molecular biology and large randomized the reader a “mini review” of basic concepts and
clinical trials. This textbook provides a review of the pathophysiology in internal medicine, allowing the
major issues in internal medicine by presenting a reader to approach clinical problems in an appro-
wide variety of typical examination questions and priate manner.
referenced answers. Finally, since the last edition was published, the
The text is organized by topic to facilitate in- list of references has been expanded and updated to
depth review but contains a large comprehensive reflect current knowledge in the field of internal
test that mimics the typical examination format. The medicine.
content has been organized to reflect the areas
tested on Step 2 of the United States Medical Yashesh Patel, MD, MSc, FRCPC
Licensing Examination (USMLE Step 2). The format Barry J. Goldlist, MD, FRCPC, FACP
of the questions is modeled after the format used on
v
Copyright © 2007 by The McGraw-Hill Companies, Inc. Click here for terms of use.
,This page intentionally left blank
, Acknowledgments
I would like to thank the countless medical students Goldlist for giving me the opportunity to work on
and residents who teach me and compel me to learn the latest edition of the book with him.
every day. Thanks to the patience of my family and
friends for putting up with my absences while I Yashesh Patel, MD, MSc, FRCPC
worked on the book. Finally, thanks to Barry
vii
Copyright © 2007 by The McGraw-Hill Companies, Inc. Click here for terms of use.