ASCP Hematology Exam-MLT
The light-colored zone adjacent to the nucleus in a plasmacyte is the:
A. ribosome
B. chromatin
C. mitochondria
D. Golgi area - ANSD. Golgi area
The majority of the iron in an adult is found as a constituent of:
A. hemoglobin
B. hemosiderin
C. myoglobin
D. transferrin - ANSA. hemoglobin
The main function of the hexose monophosphate shunt in the erythrocyte is to:
A. reglate the level of 2,3-DPG
B. provide reduced glutathione to prevent oxidation of hemoglobin
C. prevent the reduction of heme iron
D. provide energy for membrane maintenance - ANSB. provide the level 2,3-DPG
In order for hemoglobin to combine reversibly with oxygen, the iron must be:
A. complexed with haptoglobin
B. freely circulating in the cytoplasm
C. attached to transferrin
D. in the ferrous state - ANSD. in the ferrous state
In which of the following disease states are teardrop cells and adnormal platelets most
characteristically seen?
A. hemolytic anemia
B. multiple myeloma
C. G-6-PD deficiency
D. myeloid metaplasma - ANSD. myeloid metaplasia
In the normal adult, the spleen acts as a site for:
A. storage of red blood cells
B. production of red blood cells
, C. synthesis of erythropoietin
D. removal of imperfect and aging cells - ANSD. removal of imperfect and aging cells
After removal of red blood cells from the circulation hemoglobin is broken down into:
A. iron, porphyrin, and amino acids
B. iron, protoporphyrin, and globin
C. heme, protoporphyrin, and amino acids
D. heme, hemoseridin, and globin - ANSB. iron, protoporphyrin, and globin
Heinz bodies are:
A. readily identified with polychrome stains
B. rarely found in glucose-6-phosphate dehydrogenase deficient erythrocytes
C. closely associated with spherocytes
D. denatured hemoglobin inclusions that are readily removed by the spleen - ANSD. denatured
hemoglobin inclusions that are readily removed by the spleen
Cells for the transport of O2 and CO2 are:
A. erythrocytes
B. granulocytes
C. lymphocytes
D. thrombocytes - ANSA. erythrocytes
Erythropoeitin acts to:
A. shorten the replication time of the granulocytes
B. stimulate RNA synthesis of erythroid cells
C. increase colony-stimulating factors produced by the B-lymphocytes
D. decrease the release of marrow reticulocytes - ANSB. stimulate RNA synthesis of erythroid
cells
What cell shape is most commonly associated with an increase MCHC?
A. teardrop cells
B. target cells
C. spherocytes
D. sickle cells - ANSC. spherocytes
Which of the following characteristics are common to hereditary spherocytosis, hereditary
elliptocytosis, hereditary stomatocytosis, and paroxysmal nocturnal hemoglobinuria?
A. autosomal dominant inheritance
The light-colored zone adjacent to the nucleus in a plasmacyte is the:
A. ribosome
B. chromatin
C. mitochondria
D. Golgi area - ANSD. Golgi area
The majority of the iron in an adult is found as a constituent of:
A. hemoglobin
B. hemosiderin
C. myoglobin
D. transferrin - ANSA. hemoglobin
The main function of the hexose monophosphate shunt in the erythrocyte is to:
A. reglate the level of 2,3-DPG
B. provide reduced glutathione to prevent oxidation of hemoglobin
C. prevent the reduction of heme iron
D. provide energy for membrane maintenance - ANSB. provide the level 2,3-DPG
In order for hemoglobin to combine reversibly with oxygen, the iron must be:
A. complexed with haptoglobin
B. freely circulating in the cytoplasm
C. attached to transferrin
D. in the ferrous state - ANSD. in the ferrous state
In which of the following disease states are teardrop cells and adnormal platelets most
characteristically seen?
A. hemolytic anemia
B. multiple myeloma
C. G-6-PD deficiency
D. myeloid metaplasma - ANSD. myeloid metaplasia
In the normal adult, the spleen acts as a site for:
A. storage of red blood cells
B. production of red blood cells
, C. synthesis of erythropoietin
D. removal of imperfect and aging cells - ANSD. removal of imperfect and aging cells
After removal of red blood cells from the circulation hemoglobin is broken down into:
A. iron, porphyrin, and amino acids
B. iron, protoporphyrin, and globin
C. heme, protoporphyrin, and amino acids
D. heme, hemoseridin, and globin - ANSB. iron, protoporphyrin, and globin
Heinz bodies are:
A. readily identified with polychrome stains
B. rarely found in glucose-6-phosphate dehydrogenase deficient erythrocytes
C. closely associated with spherocytes
D. denatured hemoglobin inclusions that are readily removed by the spleen - ANSD. denatured
hemoglobin inclusions that are readily removed by the spleen
Cells for the transport of O2 and CO2 are:
A. erythrocytes
B. granulocytes
C. lymphocytes
D. thrombocytes - ANSA. erythrocytes
Erythropoeitin acts to:
A. shorten the replication time of the granulocytes
B. stimulate RNA synthesis of erythroid cells
C. increase colony-stimulating factors produced by the B-lymphocytes
D. decrease the release of marrow reticulocytes - ANSB. stimulate RNA synthesis of erythroid
cells
What cell shape is most commonly associated with an increase MCHC?
A. teardrop cells
B. target cells
C. spherocytes
D. sickle cells - ANSC. spherocytes
Which of the following characteristics are common to hereditary spherocytosis, hereditary
elliptocytosis, hereditary stomatocytosis, and paroxysmal nocturnal hemoglobinuria?
A. autosomal dominant inheritance
