NUR 2474 Pharmacology for Professional Nursing 2024 – Examination Blue Print –Exam #1 THE INSIDER INFORMATION: THE INSIDE SCOOP

NUR 2474 Pharmacology for Professional Nursing 2024 – Examination Blue Print – Exam #1 THE INSIDER INFORMATION: THE INSIDE SCOOP Definitions to know: • Classification • Prototype • Generic Name • Brand Name • Pharmacodynamics • Pharmacokinetics • Half-life • Onset • Peak • Duration • Agonist • Antagonist • Peak • Trough • Nursing Process: Assessment, Analysis (Diagnosis), Plan, Implement, Evaluate (Know how this process applies to the process of medication administration -think like a nurse) • Anaphylaxis • Central Nervous System • Peripheral Nervous System • Sympathetic Nervous System (Know that adrenaline is really “norepinephrine” and this is the main neurotransmitter of the SNS) • Adrenergic (Know that adrenaline is really “norepinephrine” and this is the main neurotransmitter of the SNS) • Parasympathetic Nervous System (know that acetylcholine is the main neurotransmitter of this system) • Cholinergic (know that acetylcholine is the main neurotransmitter of this system) • Competitive inhibition • Non -competitive inhibition • Selectivity • Non -selectivity • Specificity • Non -specificity Know the differences in pharmacokinetics and pharmacodynamics in these populations: • Elderly • Pregnant • Breastfeeding • Children and Infants • Neonates Medications: For all medications in the table below, know the following (you have already studied : a. Classification b. Therapeutic use c. How does it work (biochemical) d. Adverse Drug Reactions e. Interventions f. Administration g. Client Instructions h. Contraindications i. Precautions j. Interactions ***For Phenytoin and Lithium, know normal levels Baclofen (Lioresal) dantrolene sodium (Dantrium) Phenytoin (Dilantin) Carbamazepine (Tegretol) Valproic Acid (Depakote, Depacon, and Depakene) Gabapentin (Neurontin) Lamotrigine (Lamictal) Topiramate (Topamax) Lidocaine (Xylocaine, esters of this are called Procaine, Novocain, Benzocain, and Americaine) Methohexital sodium (Brevital) Amphetamine/dextroamphetamine sulfate (Adderall) Methylphenidate (Ritalin/Concerta) and dexmethylphenidate (Focalin) Modafinil (Provigil) and Armodafinil (Nuvigil) Levodopa/Carbidopa (Sinemet) Primapexole (Mirapex Donepezil (Aricept) and rivastigmine (Exelon) and alantamine (Razadyne) Memantine (Namenda) Interferon beta - 1a (Avonex and Rebif) and interferon beta -1b (Betaseron) Sumatriptan (Imitrex) and zolmitriptan (Zomig) Diazepam and Lorazepam and Clonazepam and Alprazolam Buspirone: Amitriptyline (others in this same category are imipramine, doxepin, protriptyline/Aventyl, amoxapine, trimipramine/Surmontil) Fluoxetine (Prozac) Others in the same category: Paroxetine (Paxil), citalopram (Celexa), excitalopram (Lexapro), Sertraline (Zoloft) Venlafaxine (Effexor XR) Others in this same category: desvenlafaixine (Pristiq) and duloxetine (Cympbalta) Phenelzine (Nardil) Others in the same category: isocarboxazid (Marplan), tranylcypromine (Parnate), selegiline transdermal (Emsam) Bupropion hydrochloride (Wellbutrin) Lithium (Lithobid) Valproate and Depakote: Chlorpromazine (Others in this same category are haloperidol, fluphenazine, thiothixene, etc…). Risperidone (Risperdal) (Others in this category include olanzapine/Zyprexa, quetiapine (Seroquel), aripiprazole (Abilify). Ziprasidone (Geodon), clozapine (Clozaril) Betaxolol (Betopic) and Timolol (Timoptic) Fentanyl (and other opioids: Morphine, Dilaudid/Hydromorphone, Oxycodone) Find this in the Neuro System Part one in ATI under “anesthesia. Laboratory Values (know these and be able to interpret them in relation to meds you have learned about) AST (aspartate aminotransferase) 5-40 units/L ALT (alanine aminotransferase) 8-20 units/L Amylase 56-90 IU/L Lipase 0-110 units/L Direct (conjugated) bilirubin 0-0.3 mg/dL Indirect (unconjugated) bilirubin 0.1-1 mg/dL Phenytoin level 10 to 20 µg/mL Lithium Level 0.6 to 1.2 mEq/L. Measurement of the serum levels should be carried out at least 6 to 12 hours after the last therapeutic dose to avoid misinterpretation of pre-distributional levels Creatinine The normal range for creatinine in the blood may be 0.84 to 1 .21 milligrams per deciliter (74.3 to 107 micromoles per liter), although this can vary from lab to lab, between men and women, and by age Creatinine Clearance Normal values are: Male: 97 to 137 mL/min (1.65 to 2.33 mL/s). Female: 88 to 128 mL/min (14.96 to 2.18 mL/s). NUR 2474 Pharmacology for Professional Nursing – Examination Blue Print – Exam #2 THE INSIDER INFORMATION: THE INSIDE SCOOP