Medical Technology (AAB): Hematology Exam Questions with correct Answers

Medical Technology (AAB): Hematology Exam Questions with correct Answers Explain the structure of a red bell cell hemoglobin. - Ans ️️ -It is composed of a globin with 2 alpha and 2 beta chains. Each chain contains a Heme group which contains a central Fe in which four oxygen group can bind What is porphyira? - Ans ️️ -A abnormal synthesis of heme What are four hemoglobin derivatives and describe details of them? - Ans ️️ -1. Oxyhemoglobin; oxygen attaches to Fe2+ replacing the water molecule. In order to carry the O2, Fe is kept in ferrous state my methemoglobin-cytochrome C reductase 2. Carboxyhemoglobin: CO has a 200x higher affinity to hemeglobin than O2. 3. Methemoglobin: ferrous Fe becomes ferric (Fe3+). MetHb cannot bind to oxygen making people with MetHb cyanotic (blue/purple discoloration) 4. Sulfhemoglobin: triggered by increase in fulfur content from sulfur containing drugs or chronic constipation. Process cannot be reversed and must be removed How does MetHb form? How is it identified? - Ans ️️ -Ingestion of nitrates induces rapid oxidation of Heme that methemoglobin reducatase cannot keep up. MetHb can be identified by its characteristic band between 630-633nm in Evelyn-Malloy method What are the characteristic colors of the hemoglobin derivatives? How can different hemoglobins be identified? - Ans ️️ -1. HbO2 = bright red