ABOR PER: Hematology Questions and Answers 2024

ABOR PER: Hematology Questions and Answers 2024 What is hemoglobin composed of? - Ans ️️ -4 heme, 4 iron, 1 globin What disorder does a defect in heme synthesis lead to? - Ans ️️ -porphyria What is the function of the enzyme methemoglobin-cytochrome C reductase in a red blood cell? - Ans ️️ -to keep iron in the ferrous state Which hemoglobin has a 200 times greater binding capacity for the hemoglobin molecule than oxygen? - Ans ️️ -carboxyhemoglobin What product is formed when ferrous iron of hemoglobin is oxidized to the ferric state? - Ans ️️ -methemoglobin Which hemoglobin derivative causes irreversible changes in the red blood cells? - Ans ️️ - sulfhemoglobin Which hemoglobin is NOT normally present in a normal adult? - Ans ️️ -Hb-S Which embryonic hemoglobin is normally found in newborns? - Ans ️️ -Hb-F What is the most abundant hemoglobin in a newborn? - Ans ️️ -Hb-F What is the molecular structure of hemoglobin S? - Ans ️️ -valine replaces glutamic acid in the 6th position of the data chain Which hemoglobin is insoluble under lowered oxygen tension? - Ans ️️ -Hb-S What laboratory test is used to confirm the specific diagnosis os sickle cell anemia? - Ans ️️ - hemoglobin electrophoresis In the solubility test foe hemoglobin S, what is the reagent responsible for the reduction of the hemoglobin molecule? - Ans ️️ -sodium dithionite In hemoglobin C, what replaces glutamic acid? - Ans ️️ -lysine