Biochemistry Exam 1 Questions With Correct Review Solution 2023

Biochemistry Exam 1 Questions With Correct Review Solution 2023 Dehydration - ANS-What condition? cottonmouth, dry flushed skin, mental confusion, fever Overhydration - ANS-What condition? nausea, vomiting, cerebral edem, convulsion, coma, death respiratory alkalosis - ANS-breathing more rapidly (hyperventilation) respiratory acidosis - ANS-when not breathing, insufficient expiration of CO2 metabolic alkalosis - ANS-from vomiting --> hypoventilation metabolic acidosis - ANS-something wrong w/ metabolism w/ inc H+ in tissues --> hyperventilation 2,3 BPG - ANS-stabilizes T-form of Hb, shifts O2 curve to the right (easier to release O2 in tissues, in hypoxemia inc levels to facilitate unloading of O2 in tissues right = easier to release O2 in tissues metabolically active tissues make more H+s = capillaries will have lower pH which facilitates unloading of O2 from Hb - ANS-lower pH causes shift of O2 curve right or left? high CO2, low pH, low O2, 2,3 BPG - ANS-What stabilizes T state of Hb? right - ANS-O2 curve shifts right or left in T state of Hb? left - ANS-O2 curve shifts right or left in R state of Hb? high O2 - ANS-What stabilizes R state of Hb? left = CO binds more tightly to heme iron than O2 = forms carboxyhemoglobin - ANS-Does CO shift O2 curve left or right? HbF - ANS-What is the major Hb in newborns? HbA - ANS-What is major Hb in adults? Vmax unchanged Km increases - ANS-How do Vmax & Km change for competitive reversible enzyme inhibitors? Vmax lowered Km unchanged - ANS-How do Vmax & Km change for noncompetitive reversible enzyme inhibitors? inhibitor forms covalent linkage w/ catalytic site - ANS-Mechanism of active-site directed irreversible inhibitors? enzyme modifies inhibitor, altered inhibitor binds tightly to active site of enzyme & can't be displaced - ANS-Mechanism of enzyme-activated irreversible inhibitors (suicide inhibitors)?...