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KREBS CYCLE /Citric Acid Cycle /TCA CYCLE
Conversion of pyruvate to acetyl CoA
Tricarboxylic Acid Cycle/Krebs Cycle: A part of the essential pathways of energy
metabolism.
History, introduction, steps/reactions.
, 2
Conversion of pyruvate to acetyl CoA
1. After pyruvate is produced from glycolysis, it enters the mitochondria to begin aerobic
respiration.
Aerobic respiration begins with the conversion of pyruvate to acetyl CoA.
2. This conversion takes place in three steps: decarboxylation, the reduction of NAD+, and
the attachment of coenzyme A.
3. This is an irreversible reaction, catalyzed by a multienzyme complex, known as pyruvate
dehydrogenase complex (PDH).
KREBS CYCLE /Citric Acid Cycle /TCA CYCLE
Conversion of pyruvate to acetyl CoA
Tricarboxylic Acid Cycle/Krebs Cycle: A part of the essential pathways of energy
metabolism.
History, introduction, steps/reactions.
, 2
Conversion of pyruvate to acetyl CoA
1. After pyruvate is produced from glycolysis, it enters the mitochondria to begin aerobic
respiration.
Aerobic respiration begins with the conversion of pyruvate to acetyl CoA.
2. This conversion takes place in three steps: decarboxylation, the reduction of NAD+, and
the attachment of coenzyme A.
3. This is an irreversible reaction, catalyzed by a multienzyme complex, known as pyruvate
dehydrogenase complex (PDH).
