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West Coast University Pathophysiology questions with correct answers
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presence of philadelphia chromosome high granulocyte count CORRECT ANSWER chronic myeloid leukemia clinical significance 15% of all leukemia cases avg age: 40-45 CORRECT ANSWER CML stats fatigue, weight loss, sweats, bleeding disorder, splenomegaly CORRECT ANSWER CML signs/symptoms responds poorly to chemo anti bcr/abl therapy bmt (bone marrow transfusion) CORRECT ANSWER CML treatment median survival ~2 years CORRECT ANSWER what happens if CML left untreated? malignant disorder associated with transformation of myeloid stem cells cells have large segmented nucleus + fine chromatin increase infection susceptibility (skin, GI, GU, respiratory) CORRECT ANSWER acute myeloid luekemia significance? 80% all cases are adults
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