TEST BANK FOR CLINICAL PHARMACOLOGY

13. A nurse would expect to administer pyrazinamide cautiously to which clients? Select all that apply. A) Clients with diabetes B) Clients with hepatic impairment C) Clients with renal impairment D) Clients with hypertension E) Clients with HIV infection Ans: A, B, C, E Feedback: Pyrazinamide should be used cautiously in clients during pregnancy and lactation and in clients with hepatic or renal impairment, HIV infection, or diabetes. 14. A nurse is preparing to teach a client about common adverse reactions associated with rifampin (Rifadin). Which of the following would the nurse include? Select all that apply. A) Discoloration of body fluids B) Vertigo C) Joint pain D) Nausea E) Rash Ans: A, B, D, E Feedback: Common adverse reactions of rifampin include nausea, vomiting, epigastric distress, heartburn, fatigue, vertigo, rash, reddish-orange discoloration of body fluids, hematologic changes, and renal insufficiency. 15. When completing the pre administration assessment for any antitubercular drug, which of the following would the nurse include? Select all that apply. A) Culture and sensitivity testing B) Complete blood count C) Family and contacts history D) Radiographic studies E) Medication history Ans: A, B, C, D, E Feedback: Pre administration assessment for any antitubercular drug should include culture and sensitivity testing, complete blood count, radiographic studies, medication history, and a family and contacts history for those with active TB. 16. A nurse is developing a plan of care for a client receiving an antitubercular drug. Which nursing diagnosis would the nurse most likely include directly related to drug therapy? Select all that apply. A) Acute Pain B) Risk of Skin Integrity C) Imbalanced Nutrition D) Body Image Disturbances E) Risk for Ineffective Self Health Management Ans: A, C, E Feedback: Drug administration–specific nursing diagnoses that may be made during treatment with antitubercular drugs include Acute Pain related to frequent injections, Imbalanced Nutrition due to gastric upset, and Risk for Ineffective Self Health Management related to indifference, lack of knowledge, and long-term treatment. 17. When developing the plan of care for a client receiving antitubercular therapy, the nurse would identify which of the following as a goal? Select all that apply. A) Client will state adverse reactions to report. B) Client will maintain adequate nutritional status. C) Client and family demonstrate an understanding of the drug regimen. D) Client manages the therapeutic regimen effectively. E) Client exhibits a negative sputum culture. Ans: A, B, C, D, E Feedback: The goals for a client taking antitubercular drugs can include identification and treatment of adverse reactions including ability to report adverse reaction, maintenance of adequate nutritional status, demonstration of understanding of the drug regimen by client and family, effective management of the therapeutic regimen by the client, and achievement of therapeutic response. 4. A nurse recognizes the class of medication being administered to help plan ongoing assessment and client education. The nurse would identify which drug as an example of a b-adrenergic blocker? Select all that apply. A) Carvedilol (Coreg) B) Propranolol (Inderal) C) Metoprolol (Lopressor) D) Atenolol (Tenormin) E) Labetalol (Trandate) Ans: B, C, D Feedback: Propranolol, metoprolol, and atenolol are b-adrenergic blockers, but carvedilol and labetalol are a/b-adrenergic blockers. 5. A nurse understands that while most b-adrenergic receptors are found in the heart, they are also commonly found in which other organs? Select all that apply. A) Pancreas B) Eyes C) Liver D) Lungs E) Skin Ans: B, D Feedback: b-adrenergic receptors are also found in the eyes and lungs. The blockage of these receptors can be beneficial in treatment of glaucoma or cause adverse reactions in the lungs (bronchospasms). 6. A nurse administers atenolol (Tenormin) to a client suffering an acute MI based on the understanding that this drug will result in which of the following changes in the client? Select all that apply. A) Increase the heart's excitability B) Decrease the heart's workload C) Increase the heart's oxygen consumption D) Decrease heart rate E) Constrict blood vessels Ans: B, D Feedback: Atenolol (Tenormin) is a b-adrenergic blocking drug. Blockade of b-adrenergic results in decreased heart rate, dilation of blood vessels, a decrease in the heart's excitability, and a decrease in cardiac workload and oxygen consumption and provides membrane-stabilizing effects.