2023-2024
abused prescription drug, second-most - ANSWER codeine
Act also known as the Controlled Substance Act (1970) - ANSWER Comprehensive
Drug Abuse Prevention and Control Act
actiq - ANSWER transmuscosal fentanyl only approved for breakthrough cancer
pain in opioid tolerant patients
addictive drugs all activate the brain's _________ - ANSWER dopamine reward
circuit
after detox, an opioid addict can be rx'd ___________ to discourage renewed opioid
abuse - ANSWER naltrexone
AIDS patients use Dronabinol (marinol) - ANSWER for appetite stim
alvimopan - ANSWER used for tx of opioid-induced ileus
amphetamines are schedule - ANSWER II
amphetamines work primarily by promoting neuronal release of _________ &
___________, and partly by blocking their reuptake - ANSWER norepinephrine;
dopamine
amphetamines, most common adverse effects - ANSWER insomnia; weight loss
analgesics, most effective available - ANSWER opioids
avinza - ANSWER extended release morphine
barbiturate OD antidote? - ANSWER none, just supportive treatment
barbiturate OD produces same classic triad of symptoms (resp. depression, coma,
pinpoint pupils) as seen with - ANSWER opioid OD
barbiturate tolerant individuals are cross-tolerant to other CNS depressants
(alcohol, benzos, general anesthetics) but not with ________ - ANSWER opioids
behavior pattern characterized by continued use of a psychoactive substance
despite physical, psychologic, or social harm - ANSWER addiction
, benzodiazepine principal indications are - ANSWER anxiety, insomnia, seizure
disorders
benzodiazepines adverse effects - ANSWER daytime sedation; anterograde
amnesia
benzodiazepines are classified as Schedule - ANSWER IV
benzodiazepines are primarily for which two anxiety d/o's - ANSWER panic
disorder, GAD
benzodiazepines produce their actions by enhancing the effects of _____, the
principal inhibitory neurotransmitter in the CNS - ANSWER GABA
benzodiazepines-like controlled substace approved for long-term use in insomnia
- ANSWER eszopiclone (Lunesta)
black box warnings - ANSWER a component of REMS
bridging agents commonly abused - ANSWER methadone, tramadol,
buprenorphine (suboxone)
buprenorphine formulations used in management of opioid addiction - ANSWER
subutex or suboxone SL
butorphanol (stadol) and nalbuphne (nubain) are contraind. In MI as they -
ANSWER increase cardiac work
butrans transdermal sites must be rotated. No site may be reused within ___ days -
ANSWER 21
cancer pain - ANSWER frequently undertreated, able to be mitigated in 90% of
cases with proper dosing/drug therapy (consider adjuvants)
chronic opioid therapy candidates can be identified with - ANSWER ORT (opioid
risk tool); SOAPP (screener and opioid assessment for patients with pain); DIRE
(diagnois, intractability, risk, and efficacy score)
chronic opioid therapy fails - ANSWER 50-70% of the time
code of fed regulations, title 21, section 1306 governs - ANSWER issuance & filling
of prescriptions
codeine by itself is a schedule ___ CS. In cough meds, it's often schedule ___ -
ANSWER II, V