WGU D027 Patho Pharm Exam Questions and Answers

How are multi-factorial diseases affected by genetics? - correct answers risk for a multifactorial trait or condition depends on how close you are to a family member with the trait or condition. (ex: if sibling has it=higher risk) Describe Hutchinson-Gilford Progeria Syndrome. Explain the signs and symptoms. How is it diagnosed and treated? - correct answers -progressive genetic disorder - children age rapidly -occurs randomly, not inherited S/S: -slow growth & hair loss in 1st/2nd year of life -short stature or slow growth -delayed tooth development or failure to develop normally -skin wrinkles/dryness -enlarged head, hearing loss, high pitched voice, incomplete sexual maturation, joint stiffness, loss of muscle, osteoarthritis, taut skin Dx: -gentic test for LMNA -physical assessment Tx: - no cure -PT/OT -Statins - decrease liver production of harmful cholesterol -NSAIDS - relieve pain and decrease inflammation -meds to strengthen/build bones PRNs for anxiety - correct answers f*cking benzos baby - alprazolam, chlordiazepoxide, clonazepam, diazepam, lorazepam What are the body's compensatory mechanisms? - correct answers - Autonomic nervous system - Cardiac rate/contractility - Venous return, vasoconstriction - Baroreceptor reflexes (homeostatic mech to maintain BP) - Chemoreceptor reflexes (regulates respiration, cardiac output, regional blood flow) What are the two recs for genetic testing? - correct answers -carrier screening - determines if a person is a carrier for specific autosomal recessive diseases