ISBB HARR(questions n answers graded A+ 2023 passed)

ISBB HARRWhich of the following distinguishes A1 from A2 blood groups? An A2 person may form anti-A1; an A1 person will not form anti-A1 A patient's serum is incompatible with O cells. The patient RBCs give a negative reaction to anti-H lectin. What is the most likely cause of these results? The patient may be a Bombay What antibodies are formed by a Bombay individual? Anti-A, B, and H Acquired B antigens have been found in Group A persons Blood is crossmatched on an A positive person with a negative antibody screen. The patient received a transfusion of A positive RBCs 3 years ago. The donors chosen for crossmatch were A positive. The crossmatch was run on the Ortho Provue and yielded 3+ incompatibility. How can these results be explained? The patient is an A2 with anti-A1 A patient's red cells forward as group O, serum agglutinates B cells (4+) only. Your next step would be: Incubate washed red cells with anti-A1 and anti-A,B for 30 minutes at room temperature Which typing results are most likely to occur when a patient has an acquired B antigen? Anti-A 4+, anti-B 1+, A1 cells neg, B cells 4+ Which blood group has the least amount of H antigen? A1B What type RBCs can be transfused to an A2 person with anti-A1? A or O What should be done if all forward and reverse ABO results as well as the autocontrol are positive? Wash the cells with warm saline, autoadsorb the serum at 4°C N-acetyl-D-galactosamine is the immunodominant carbohydrate that reacts with: Dolichos biflorus A stem cell transplant patient was retyped when she was transferred from another hospital. What is the most likely cause of the following results? Patient cells: Anti-A, neg Anti-B, 4+ Patient serum: A1 cells, neg B cells, neg Immunodeficiency What should be done if all forward and reverse ABO results are negative? Incubate at 22°C or 4°C to enhance weak expression What reaction would be the same for an A1 and an A2 person? Positive reaction with anti-A,B A female patient at 28 weeks' gestation yields the following results: Patient cells: Anti-A, 3+ Anti-B, 4+ Patient serum: A1 cells, neg B cells, 1+ O cells, 1+ Alloantibody in patient serum Which condition would most likely be responsible for the following typing results? Patient cells: Anti-A, neg Anti-B, neg patientserum: Weak or excessive antigen(s) Which of the following results is most likely discrepant? Anti-A, neg Anti-B, 4+ A1 cells, neg B cells, neg Negative A1 cells A 61-year-old male with a history of multiple myeloma had a stem cell transplant 3 years ago. The donor was O positive and the recipient was B positive. He is admitted to a community hospital for fatigue and nausea. Typing results reveal the following: Anti-A = 0 Anti-B =0 Anti-A,B = 0 Anti-D = 4+ A1 cells = 4+ B cells = 0 How would you report this type? Undetermined A complete Rh typing for antigens C, c, D, E, and e revealed negative results for C, D, and E. How is the individual designated? Rh negative How is an individual with genotype Dce/dce classified? Rh positive If a patient has a positive direct antiglobulin test, should you perform a weak D test on the cells? No, the cells are already coated with antibody Which donor unit is selected for a recipient with anti-c? r´ry Which genotype usually shows the strongest reaction with anti-D D-/D- hy is testing for Rh antigens and antibodies different from ABO testing? ABO reactions are primarily due to IgM antibodies and usually occur at room temperature; Rh antibodies are IgG and agglutination usually requires a 37°C incubation and enhancement media Testing reveals a weak D that reacts 1+ after indirect antiglobulin testing (IAT). How is this result classified? Rh-positive What is one possible genotype for a patient who develops anti-C antibody? rr A patient developed a combination of Rh antibodies: anti-C, anti-E, and anti-D. Can compatible blood be found for this patient? rr blood could be used without causing a problem A patient tests positive for weak D but also appears to have anti-D in his serum. What may be the problem? A D mosaic may make antibodies to missing antigen parts Which offspring is not possible from a mother who is R1R2 and a father who is R1r? DcE/DcE