Galen NUR 210 Exam 1 Modules 1-3 Rated 100% Correct!!

Pharmacokinetics - The process in which medications move through the body What are the 4 phases of pharmacokinetics? - absorption, distribution, metabolism, excretion Absorption - happens with drug movement from the GI tract into the bloodstream. Most meds are taken by mouth. Oral absorption - Takes awhile to get absorbed because it has to go through the GI system Usually takes 2-4 hours •Enteric coated aspirin - hard on stomach can not crush pill •Extended release absorbed in the small intestine IM absorption - Absorbed 1-2 hours IV absorption - Absorbed 30-60 minutes dissolution - Dissolution happens when a po medication breaks down into particles, disintegrates, and dissolves to combine with liquid so absorption from the GI tract into the bloodstream occurs. Liquid medications are absorbed faster than solids. Food can interfere with the absorption of drugs. Drugs that resist dissolution - Parenteral medications (SL, eyedrops, inhalants, transdermal) do not pass through the GI tract.Enteric coated medications are designed to resist disintegration until the pill reaches the small intestine. EC and sustained release meds should not be crushed. Factors that affect absorption - •Lack of muscle and increased fat changes medicine absorption •Food consumption - will change medicine potency (delayed) •Stress - Exercise, medicine goes to muscle •pH - Medicine is made for acidic environments •Antacid changes absorption •Taken alone so it doesn't change the action