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samenvatting college CVZ

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samenvatting college CVZ

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Uploaded on
August 29, 2023
Number of pages
13
Written in
2019/2020
Type
Summary

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CVZ hoorcollege 1
Geneesmiddelen – werken op celniveau
Effect op organen en orgaansystemen
Behandeling van ziekten en voorkomen
Symptoombestrijding
Geneesmiddelen – farmacologische groepen




!!!

Werking van cellen en farmacologie




!!!

Farmacologische groepen
- Calciumkanaalblokkers
- Selectieve – B2 – agonisten
- ACE-remmers
- Beta-blokkers
- Hormonen
- NSAID’s
- Selectieve serotonine heropname remmers

, Eiwitten aangrijpingspunten
- 20.000 verschillende eiwitten
- Elk orgaan heeft zijn eigen specifieke eiwitten
- 1% van de eiwitten is geschikt als aangrijpingspunt
- 200 verschillende soorten farmacologische groepen
- Bevinden zich op het celmembraan – receptoren
- Bevinden zich in de cel (intracellulaire receptoren)

Receptoren = aangrijpingspunten




Geneesmiddelen binden op receptoren
- Atenolol = verlaagt de hartslag en bloeddruk
- Salbutamol= verwijdt de luchtwegen
- Morfine = blokkeert pijnbanen in het ruggenmerg

Binding op receptoren is specifiek




Geneesmiddelen bootsen chemische boodschappers na
- Hormonen
- Neurotransmitters
- Mediatoren

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