USMLE Step 1 Questions & Answers Solved 100%

Hormone to test for menopause. - Answer high FSH Treatment of Heparin Induced Thrombocytopenia - Answer Direct thrombin inhibitors-Agatroban Then protamine sulfate PT or PTT for Heparin - Answer PTT PT or PTT for Warfarin - Answer PT Skin necrosis from warfarin, what do you do? - Answer Give heparin Antidote to excessive thrombolytics - Answer Aminocaproic acid Glanzmanns Thrombasthenia - Answer GPIIb/IIIa- platelet adhesion Bernard soulier - Answer Gp1b Aspirin decreases platelet adehsion, activation or aggregation? - Answer Activation Drugs that decrease platelet activation - Answer aspirin, toclopidine, clopidogrel- block ADP receptors Drugs that decrease aggregation - Answer abciximab, eptifibatide, tirofiban Why do sulfonamides decrease increase PT in patients on warfarin? - Answer Sulfonamides displace the weakly but extensively bound warfarin on plasma proteins. This is different mechanism from cimetidine which increase P450 Onset, peak effect and duration of lispro - Answer onset: 0.3-0.5hrs peak effect: 1-2 hrs duration: 2-4hrs Onset peak effect and duration of regular - Answer onset: 0.5-1hrs peak effect: 2-4hrs duration: 5-7hrs