Handling Hazardous Drugs | Questions and Answers with complete solution

Why drugs are labeled as hazardous - toxicity risk to healthcare workers who could come into contact with the drug Three categories of hazardous drugs - antineoplastics non-antineoplastics (hormones, transplant drugs) drugs with reproductive risks Characteristics that make a drug hazardous - carcinogenic teratogenic have reproductive toxicity organ toxicity at low doses genotoxic (damage DNA and can cause cancer) NIOSH - National Institute for Occupational Safety and Health NIOSH duty - determines which drugs are hazardous NIOSH List of Antineoplastic and Other Hazardous Drugs in the Healthcare Setting USP and hazardous drugs - USP 800, sets standards on how to work safely with hazardous drugs Federally enforcable December 2019 adds to but does not replace 795 and 797 Drugs that require special handling to avoid toxicity to works - Antineoplastics Drugs with reproductive risks Hormones Transplant drugsOthers Drugs with reproductive risks - Pregnancy category X Many category C and D - paroxetine, methotrexate, misoprostol, mifepristone, ribavirin, 5-alpha reductase inhibitors (dutasteride, finasteride)