Kaplan and Sadock's Chapter 13 & 26 from Study Guide questions with correct answers

13.1. Which of the following statements about the dopamine hypothesis of schizophrenia is true? A. Dysregulation of dopaminergic neurotransmission is caused by postsynaptic sensitivity. B. Dopamine release caused by amphetamine challenge is higher during remission. C. Higher amphetamine-provoked dopamine release predicts worsening of psychotic symptoms. D. Overactivity of dopamine in the subcortical basal ganglia contributes to negative symptoms. E. There is a lower occupancy of D2/3 receptors in relapsed patients. Answer C. Higher amphetamine-provoked dopamine release predicts worsening of psychotic symptoms. 13.2. True statements about hypothesized neurobiological models of schizophrenia include A. Genes function in part by increasing vulnerability to environmental factors. B. Environmental factors increase risk by producing subtle brain damage. C. The apparent lack of gliosis in postmortem studies implicates in utero factors. D. As the prefrontal cortex matures, behavioral and cognitive sequelae of subtle structural deficits become manifest. E. All of the above Answer E. All of the above 13.3. With regard to the ventricular size in schizophrenia, which of the following statements is true?