USMLE Practice Questions and answers

Diphenhydramine toxicity - sedation, antimuscarinic, anti alpha adrenergic DNA from three vesicles on a person infected with HSV, when treated with restriction enzymes will show what pattern of bands? - all bands will be identical pt has fever, hx of several pyelonephritis, urosepsis, anemia, painful renal masses that are yellow with necrotic center, epitheloid with partially clear and granular to foamy cells, bacterial culture positive for proteus - xanthogranulomatous pyelonephritis kid likes to run outside with no shoes, becomes lethargic and is found to have iron deficiency anemia, what does he have and what do you treat him with? - ancylostoma duodenale, necator americanus (hookworms) treat with bedazzles or pyrantel pamoate presbycusis - high frequency hearing loss d/t destruction of hair cells at cochlear base how does a 6yo boy view death - as final what can be used to increase a pt's leukocyte count for pt going through chemotherapy? - Filgrastim Sargramostim treatment for oral thrush - nystatin "swish and swallow" blood marrow smear shows mature megakaryocytic hyperplasia - ITP study in which pts are split among groups with varying doses of the drug and then assessed - open labeled clinical trial what biochemical process does malonylCoA inhibit - fatty acid oxidation microcytic anemia in pt with low hematocrit and low Hb - iron deficiency anemia, chronic blood loss child's chest shows pectus carinatum and beading of costochondric joints - rickets, vit D deficiency lymphatic drainage of dorsolateral foot - popliteal fossa mechanism of action of sulfonylurea - triggers release of insulin by closing K+ channel in beta cell membrane, so cell depolarizes via increased Ca++ influx pt with sickle cell, acute painful enlargement of spleen, hypotension, tachycardia - splenic sequestration crisis caused by intrasplenic trapping of red cells nandrolone - anabolic steroid fish that is really high in mercury - swordfish, shark, marlin air fluid level on left side of chest, elevation of stomach bubble, mediastinum in midline - hemopneumothorax, not under tension tramadol - used for chronic pain; weak opioid agonist, also inhibits serotonin and NE uptake