NR 567 Week 5 Discussion; Case Scenario Discussion; Addison’s Disease Medication

NR 567 Week 5 Discussion; Case Scenario Discussion; Addison’s Disease Medication Addison's Disease Medication 1. Write out the order including the pharmaceutical agent, dose, route and when it should be given. Large amounts of parenteral hydrocortisone in addition to correction of fluid and electrolyte abnormalities. Hydrocortisone sodium succinate or phosphate in doses of 100mg IV can be given every 8 hours until stable. The dose is gradually reduced to achieve maintenance dosage in approximately 5 days. Hydrocortisone 100 mg IV bolus, followed by 50 mg IV every 6 hours. Patient can also receive 200 mg/24 hours as a continuous IV infusion for the first 24 hours. IV bolus of NS %0.9 is recommended as well. Hydrocortisone 50 mg IV bolus is administered every six hours until vital signs are within normal limits (WNL) and ability to eat and take medication per oral (PO). For long-term: Fludrocortisone: Oral: Initial: 0.05 to 0.1 mg once daily in the morning (in combination with hydrocortisone or cortisone). Usual maintenance dose: 0.05 to 0.2 mg once daily. 2. Justify the rationale on why this medication was selected in this particular situation. It rapidly decreases the inappropriate vasopressin production with increased clearance of free water and correction of hyponatremia. A glucocorticoid is the first choice for the management of adrenal insufficiency. Hydrocortisone is a shirt-acting glucocorticoid and is generally considered to be the better choice for a short-acting glucocorticoid regimen, according to Nieman (2021).