HMX Immunology Final Exam Study Guide complete guiding exam update

Tissue resident sentinel cells include (3 types) - Dendritic cells, macrophages, and mast cells Circulating leukocytes involved in innate response (2 types) - Monocytes and neutrophils Phagocytic immune cells (2 types) - Macrophages and neutrophils Difference between macrophages and neutrophils? - Neutrophils are short lived and will undergo apoptosis after eating a microbe; macrophages are longer-lived and will eat apoptotic cells and waste General cytokine role in innate immune response (and what cells release them?) - Released by dendritic cells, macrophages, and mast cells. Pro-inflammatory molecules that interact with blood vessel endothelium to recruit circulating leukocytes, fluid, and proteins into tissue Which tissue-resident sentinel cell will release histamine upon activation? - Mast cell Cytokines promote up-regulation of what kind of molecule within blood vessel walls? - Adhesion molecules E-Selectin - An adhesion molecule that helps to slow down circulating leukocytes in innate immune response (low-affinity interaction) E-Selectin Ligand - A ligand expressed by circulating leukocytes that helps them stick to blood vessel endothelium in innate immune response ICAM-1 - An adhesion molecule that helps ci