Integrated Exam 1 Practice Questions and Answers Latest 2022/2023

Integrated Exam 1 Practice Questions and Answers Latest 2022/2023 (All correct answers are indicated on top of every question) B.) Ingestion The most common route of accidental exposure to toxicants in toddlers is: A.) Inhalation B.) Ingestion C.) Contact (skin, etc.) D.) Puncture wounds E.) Other E.) a and c Forensic toxicology requires the participation of: A.) Poison control center B.) Emergency personnel C.) Crime lab D.) a and b E.) a and c E.) c and d Toxicogenetics may explain: A.) The response of population groups to major toxicants B.) The cellular response to the toxicant C.) Idiosyncratic reactions D.) The development of individualized therapies E.) c and d E.) b and d A toxicant that is inhaled: A.) Will never get in the bloodstream B.) Can be stored in the liver C.) Is exclusively eliminated by the lungs D.) Can be eliminated by the kidneys E.) b and d D.) a and b Intoxications in the elderly can be worsened by: A.) Irregular eating habits B.) Impaired kidney function C.) Undeveloped blood-brain barrier D.) a and b E.) All of the above B.) A synergistic effect A drug combination whose toxic effect can be described as (5+5=30) refers to: A.) Potentiation B.) A synergistic effect C.) An additive effect D.) a and b E.) a and c D.) When two chemicals counterbalance each others effect in the same physiologic function Functional antagonism describes: A.) The interaction of two substances that react generating an inactive product B.) The prevention of the absorption of a compound by another C.) Increased metabolism of the toxic compound induced by another compound D.) When two chemicals counterbalance each others effect in the same physiologic function E.) When a chemical blocks the binding of another to its receptor D.) a and b The quantal response: A.) Is by definition an all or non response B.) Has a bell-shaped curve C.) Is linear through a dose range D.) a and b E.) a and c E.) b and c The curve describing the response to essential nutrients: A.) Is sigmoidal B.) Is U-shaped C.) Is also called hormesis D.) Is shaped as a bell E.) b and c A.) Have the same efficacy Two drugs that have the same ED50: A.) Have the same efficacy B.) Have the same potency C.) Will have the same therapeutic index D.) Will have the same margin of safety E.) None of the above C.) Is irreversible Damage to the CNS: A.) Can be reversible B.) Always leads to cancer C.) Is irreversible D.) a and b E.) b and c C.) Chronic exposire to benzene A delayed toxicity can include: A.) Corrosive damage to the esophagus B.) Inhalation of chlorine C.) Chronic exposire to benzene D.) a and c E.) b and c D.) a and b Side effects of therapeutic drugs: A.) Can be broad B.) Are always undesirable C.) Are always unpredictable D.) a and b E.) b and c E.) a and c Allergic reactions: A.) Follow a classic toxic dose-response B.) Are commonly elicited by non-protein chemicals C.) Require sensitization D.) a and b E.) a and c D.) b and c An unconscious patient that became intoxicated by ingestion of insecticide: A.) Requires immediate dilution of the poison B.) Needs vital signs (pulse, breathing) determined C.) Needs only to be transported to the ER D.) b and c E.) All of the above B.) Respiratory, cardiovascular, and CNS The major signs to monitor in the intoxicated patient are: A.) Cardiovascular, CNS, and liver B.) Respiratory, cardiovascular, and CNS C.) Respiratory, cardiovascular, and renal D.) Cardiovascular, renal, and liver E.) Cardiovascular and respiratory B.) Administer CPR The most effective way to reverse an arrhythmia in the intoxicated patient is to: A.) Give sodium bicarbonate by iv B.) Administer CPR C.) Give Lidocaine by iv D.) Administer Procainamide E.) Wait until the arrhythmia subsides spontaneously B.) Resuscitation can exceed 30 minutes In the management of the respiratory function of an intoxicated patient: A.) Administration of Doxapram is the first resort B.) Resuscitation can exceed 30 minutes C.) Never use 100% oxygen D.) a and b E.) b and c E.) a, b, and c The management of the CNS function in the intoxicated patient: A.) Is aimed at preventing coma and convulsion B.) Is specific to the toxic agent C.) Can use Diazepam as anticonvulsant D.) a and b E.) a, b, and c E.) a and b Mydriasis is a common sign of: A.) Severe CNS depression B.) Opiates overdose C.) Intoxication with organo phosphate compounds D.) Sarin gas exposure E.) a and b C.) Is not informative An intoxicated patient that presents hypothermia: A.) May have overdosed with salicylates B.) Was exposed to anticholinergic agents C.) Is not informative D.) Overdosed with antihistamines E.) a and d E.) All of the above The management of ingested toxicants in the GI tract can be accomplished by: A.) Gastric lavage B.) Cathartics C.) Neutralization D.) Poison adsorption E.) All of the above B.) To determine corneal damage The use of 2% Fluorescein in the eye exposed to toxicants is: A.) To neutralize the toxic agent B.) To determine corneal damage C.) To repair corneal damage D.) b and c E.) None of the above E.) c and d Gastric emptying by emesis: A.) Is recommended when dealing with corrosive intoxication B.) Can be performed safely in children C.) Can result in pneumonia in the case of ingestion of petroleum products D.) Is not recommended E.) c and d E.) Never. It's only effective up to 4-6 hours post-intoxication Gastric lavage can be performed after 6 hours of intoxication if: A.) The patient ingested corrosives B.) The patient is at high risk of seizures