Chapter 12: Anti-inflammatory, Antarthritics, and Antigout Drugs Vislosky: Introduction to Clinical Pharmacology, 9th Edition

MULTIPLE CHOICE 1. A patient with joint inflammation is prescribed an anti-inflammatory drug. The patient asks you how this drug works to address this problem. What is your best response? a. “Anti-inflammatory drugs reduce pain and limit blood vessel responses to joint injury.” b. “Anti-inflammatory drugs contain antibacterial and anti-inflammatory properties.” c. “Anti-inflammatory drugs limit the body’s response to cortisol in the body.” d. “Anti-inflammatory drugs increase the release of TNF and other mediators.” ANS: A Anti-inflammatory drug’s primary purpose is to reduce pain and prevent or limit the tissue and blood vessel responses to injury or invasion. DIF: Cognitive Level: Applying REF: p. 227 2. A patient with a history of cardiovascular disease has been prescribed aspirin daily. What specific risk should this patient be informed of because of taking aspirin? a. Risk of infection b. Risk of bleeding c. Risk of liver impairment d. Risk of cognitive impairment ANS: B Patients who take aspirin must be monitored for bleeding due to irreversible platelet inhibition for the lifespan of the platelet so as long as 7 to 8 days. DIF: Cognitive Level: Applying REF: p. 228 3. A male patient taking daily aspirin for the prevention of cardiovascular complications informs you that he is planning to have a tooth extraction next week. What correct information should be provided to this patient? a. “Notify your healthcare provider and stop taking the aspirin before the dental procedure.” b. “You may require aspirin plus additional pain drug after the dental procedure.” c. “Taking enteric-coated aspirin ensures you will not be at risk for any complications.” d. “Aspirin is associated with tooth loss following dental surgery.” ANS: A Patients who take aspirin must be monitored for bleeding due to irreversible platelet inhibition for the lifespan of the platelet as long as 7 to 8 days. This is very important if a patient is scheduled for an invasive procedure or surgery so make sure to notify the prescriber if the patient has an upcoming surgery. DIF: Cognitive Level: Applying