Chapter 15: Drugs for Immunization and Immunomodulation Vislosky: Introduction to Clinical Pharmacology, 9th Edition

MULTIPLE CHOICE 1. Which type of immunity serves to protect against day-to-day pathogen exposure? a. Innate immunity b. Natural immunity c. Acquired immunity d. Supplemental immunity ANS: A Innate immunity helps protect you from smaller day-to-day exposures to pathogenic organism but cannot provide long-term immunity to any single specific disease-causing microorganism. DIF: Cognitive Level: Remembering REF: p. 280 2. In acquired immunity, what is the body’s response to antigen exposure? a. The body initiates the clotting cascade. b. The body produces additional antigens. c. The body produces an antibody response. d. The body increases antigen response through lymphocyte action. ANS: C Exposure to antigens is the trigger for lymphocytes to begin producing antibodies. These antibodies can be made in such high amounts that, when you are re-infected by the same microorganism, they attack and destroy it or rid the body of it before it can make you sick again. DIF: Cognitive Level: Knowing REF: p. 281 3. Which of the following is an example of acquired passive immunity? a. Immunity developed from microorganism exposure through vaccination. b. Premade antibodies are transferred to you by another person or an animal. c. Microorganism exposure that makes you sick, and then develop antibodies. d. A pregnant woman who transfers antibodies to her baby during breast-feeding. ANS: D Natural acquired passive immunity is composed of the antibodies that a woman transfers to her fetus during pregnancy and to her infant during breast-feeding. This immunity is short-term but critically important in preventing young infants from many illnesses during the first 6 months after birth. DIF: Cognitive Level: Knowing REF: p. 282 4. Which type of vaccine contains antigens that are killed by heat, radiation, or chemicals? a. A toxoid b. An antiserum c. Inactivated vaccine d. Attenuated vaccine