Chapter 13: Drugs for Gastrointestinal Problems Vislosky: Introduction to Clinical Pharmacology, 9th Edition

Chapter 13: Drugs for Gastrointestinal Problems Vislosky: Introduction to Clinical Pharmacology, 9th Edition MULTIPLE CHOICE 1. What types of drugs prevent or control nausea and vomiting? a. Antiemetic drugs b. Antimotility drugs c. Antidiarrheal drugs d. Ant propulsion drugs ANS: A Antiemetic drugs control nausea and prevent vomiting. Nausea and vomiting often occur together, and the same drugs are used for both problems. DIF: Cognitive Level: Remembering REF: p. 242 2. Which common drug for nausea and vomiting is a 5-HT3 receptor antagonist? a. Ondansetron b. Promethazine c. Scopolamine d. Metoclopramide ANS: A Ondansetron (Zofran, Zuplenz) is a 5-HT3 receptor antagonist that reduces or halts nausea and vomiting by blocking serotonin (5-HT3) receptors in the intestinal tract. DIF: Cognitive Level: Knowing REF: p. 243 3. What specific problem can develop in a patient who has been prescribed both a 5-HT3 receptor antagonist and a phenothiazine? a. Bleeding b. Muscular tremors c. Serotonin syndrome d. Cardiac dysrhythmias ANS: D When combined with phenothiazine drugs, the patient may experience cardiac dysrhythmias. DIF: Cognitive Level: Knowing REF: p. 244 4. You are caring for a patient who is taking a substance P/neurokinin1 (NK1) receptor antagonist. Which laboratory finding would suggest the patient is experiencing an adverse reaction to this class of drugs? a. Decreased magnesium level b. Increased blood glucose level c. Increased serum creatinine level d. Decreased white blood cell count