SELECTIVE MAJOR DEPRESSIVE ANTIDEPRESANTS REVISION QUIZES

SELECTIVE MAJOR DEPRESSIVE ANTIDEPRESANTS
REVISION QUIZES
Nikelson
Pierre
Course NURS-6630F-4/NURS-6630N-4/NURS-6630C-4-Approaches to
Treatment-QTR-Term-wks-1-thru-11-(03/01/2021-05/16/2021)-
PT27
Test Midterm Exam - Week 6
Started 4/7/21 7:23 PM
Submitted 4/7/21 9:43 PM
Due Date 4/12/21 1:59 AM
Status Completed
Attempt 80 out of 100 points
Score
Time 2 hours, 20 minutes out of 2 hours and 30 minutes
Elapsed
Results Feedback
Displayed
 Question 1
Choose the correct option regarding the major classes of GABA receptors and the ions
involved in inhibition of the neurotransmitter pathway


Response “GABAB receptors, akin to the metabotropic glutamate receptors, are G-
Feedback: protein-coupled receptors rather than ion channels. Activation of GABAB
causes downstream changes in potassium (K+) and Ca+2 channels,
largely via G-protein-mediated inhiation of cAMP.”

 Question 2
Close-ended questions will help identify when patients are taking medications incorrectly.



 Question 3
What is the therapeutic plasma level of carbamazepine?



 Question 4
Which of the following statements below is NOT considered an appropriate treatment
strategy for treatment-resistant depression?


Response “Combination of an SSRI OR an SNRI with a norepinephrine-dopamine
Feedback: re-uptake inhibitor (bupropion) or a serotonin-norepinephrine
antagonist (mirtazapine or mianserin) is a commonly used combination”

 Question 5
Which of the following medications used for treatment of bipolar disorder may increase
stroke risk among older patients, particularly those with dementia?

, Response “Notably, pharmacovigilance studies suggest that atypical
Feedback: antipsychotics may increase stroke risk among older patients,
particularly those with dementia, so use of SGA requires more caution in
this group.”

 Question 6
Which antiepileptic drugs should we avoid in pregnant women in the treatment of bipolar
disorder?

i. Depakote
ii. Lamotrigine
iii. Topiramate
iv. Carbamazepine
v. Gabapentin

Response All the others listed except for lamotrigine are not used in
Feedback: treatment of bipolar disorder.

 Question 7
Which neurotransmitter is considered the major inhibitory neurotransmitter?



 Question 8
Choose the appropriate statement regarding lamotrigine dosing.


Response Carbamazepine induced metabolism of lamotrigine – increase dose of
Feedback: lamotrigine; Valproate may inhibit clearance of lamotrigine, so dose
reduction of lamotrigine is needed

 Question 9
Of the following antipsychotic medications listed below, which one has a Black Box
Warning for seizure, agranulocytosis, and seizures?


Response Box 7-5 * indicated clozapine-specific black
Feedback: box warnings

 Question 10
K. T. is a 35-year-old woman who was diagnosed with Generalized Anxiety Disorder about
4 weeks ago. She was prescribed Clonazepam 2 mg at bedtime but was referred to you
to determine chronic treatment. K. T. states the new medication has been helping a lot
but worries about all the side effects that come with it. She wants to discontinue the
medication. What is the appropriate next step to help K. T.?


Response “The regular use of benzodiazepines for more than 2 to 3 weeks may be
Feedback: associated with physiological dependence and the potential for
significant withdrawal symptoms with discontinuation. Discontinuation of
benzodiazepines is best done with a gradual taper to minimize
withdrawal symptoms.”
- Answer choice A: Honor the patient’s request of discontinuing the
medication.
- Answer Choice C: An abrupt stop of a benzodiazepine will likely send