NSG6005 Week 2 Quiz Bank Ch: 2, 5, 6, 10, 13

Chapter 2: Review of Basic Principles of Pharmacology ____ 1. A patient’s nutritional intake and lab work reflects hypoalbuminemia. This is critical to prescribing because: A. Distribution of drugs to target tissue may be affected ____ 2. Drugs that have a significant first-pass effect: C. Are rapidly metabolized by the liver and may have little if any desired action ____ 3. The route of excretion of a volatile drug will likely be: B. The lungs ____ 4. Medroxyprogesterone (Depo Provera) is prescribed IM to create a storage reservoir of the drug. Storage reservoirs: C. Increase the length of time a drug is available and active ____ 5. The NP chooses to give cephalexin every 8 hours based on knowledge of the drug’s: B. Biological half-life ____ 6. Azithromycin dosing requires the first day’s dose be twice those of the other 4 days of the prescription. This is considered a loading dose. A loading dose: A. Rapidly achieves drug levels in the therapeutic range ____ 7. The point in time on the drug concentration curve that indicates the first sign of a therapeutic effect is the: C. Onset of action ____ 8. Phenytoin requires a trough level be drawn. Peak and trough levels are done: D. To determine if a drug is in the therapeutic range ____ 9. A laboratory result indicates the peak level for a drug is above the minimum toxic concentration. This means that the: B. Concentration will produce an adverse response