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Advanced Pharmacology (NURS 5334) Mary Davis, DNP, MSN, ANP-BC, ADM-BC.

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Advanced Pharmacology (NURS 5334) Mary Davis,
DNP, MSN, ANP-BC, ADM-BC




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Running head: SEIZURE CASE STUDY 1




Seizure Case Study
Sally Chambless
The University of Texas at Arlington
College of Nursing and Health Innovation




In partial fulfillment of the requirements of
Advanced Pharmacology (NURS 5334)
Mary Davis, DNP, MSN, ANP-BC, ADM-BC
June 9, 2018




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SEIZURE CASE STUDY 2


5334 CASE SUMMARY TABLE
 Symptoms: List two pertinent signs and symptoms or risk factors


 Generalized tonic-clonic (GTC) seizures are manifested by convulsive episodes and a

loss of consciousness. The motor effects are two-sided and start with short sustained

contractions of muscles followed by stiffness and rhythmic jerking movements (Wells,

Schwinghammer, DiPiro, & DiPiro, 2017, p. 532). The patient may have a loss of bowel

and/or bladder control, a tendency to bite their tongue, or become cyanotic due to low

oxygen saturations (Wells et. al., 2017, p. 532). GTC seizures are commonly followed

by periods of intense sleep (Wells et. al., 2017, p. 532).

 Enzyme-inducing antiepileptic drugs (AED), such as carbamazepine, can decrease the

efficacy of other frequently prescribed drugs in the elderly (Ferlazzo, Sueri, Gasparini,

& Aguglia, 2016). Therefore, a 68-year-old male on carbamazepine monotherapy would

be at risk of drug-drug interaction if being treated with glucocorticoids, anticoagulants,

analgesics, antiretrovirals, statins, antihypertensives, or immunosuppressants (Ferlazzo

et. al., 2016). Osteoporosis is widely found in those aged 65 and over and epilepsy

increases the risk for fractures and seizure-related injuries due to poor bone health;

carbamazepine may reduce bone density by decreasing vitamin D metabolism (Ferlazzo

et. al., 2016).




 Recommended Drugs:
List three recommended drugs as indicated for this diagnosis


1. Lamotrigine (Lamictal) (Burcham & Rosenthal, 2016, p. 224)




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