MAIN TOPIC
SUBTOPIC
Additional Information
BULLET LEGENDS:
📑
☑ -PowerPoint Presentation
🔊-Module Packet/Neo Notes
- Additional Discussions/.l
BLEEDING TIME
In order to detect qualitative platelet abnormalities, platelet function
tests are designed for patients who are experiencing symptoms of Two methods under Bleeding Time:
mucocutaneous bleeding. Platelet count is an essential laboratory
test to perform before the analysis of platelet function since DUKE METHOD
thrombocytopenia is the common cause of hemorrhage.
Platelet morphology is also noted in cases of Bernard-Soulier ☑first described by Duke in 1912
Syndrome which reveals large gray platelets on the peripheral blood ● involves the use of a lancet to make an incision either on the
smear and thrombocytopenia. Only in the presence of bleeding finger or on the earlobe. A drop of blood is blotted on to the
symptoms and a platelet count that exceeds 50,000/uL is suggestive filter paper every 30 seconds until the blood ceases to flow.
of qualitative platelet disorders. ● This is not a recommended method because it is not precise
or accurate.
Principle: IVY METHOD
☑The bleeding time is the time it takes for a small standardized
wound, introduced into the capillary bed of the finger or ☑modified by Ivy in 1941
earlobe, to stop bleeding. ● involves the use of a blood pressure cuff inflated at 40
This test reflects both platelet number and platelet functional mmHg. In this method, two separate cuts in the forearm 5
integrity. It is dependent upon the elasticity of the skin and capillary cm below the fold of the elbow are made and blood is blotted
vessels, the efficiency of the tissue fluids and the mechanical and on to the filter paper every 30 seconds until the bleeding
chemical action of thrombocytes. stops.
● The length of time required for the bleeding to stop is
recorded as the bleeding time.
, FACTORS AFFECTING BLEEDING TIME: ● a blade is placed in a special handle such that when
🔊
1. Intercapillary pressure the template is placed on the forearm, the blade
Duke method is more affected by intercapillary method would make an incision having a standardized depth
since the procedure in Duke method is not standardized as and length
compared with Ivy method.
🔊
2. Size and depth of the wound
Depending on the age we have the recommended
puncture:
Children & Adults: 2.4mm-3mm
Infants: 1.6mm
3. Efficiency of the tissue fluids in accelerating the clotting
process
🔊
4. Thickness and vascularity of the skin
Avoid heavily callous sites
🔊
5. Chemical and mechanical actions of platelets
Bleeding time may also be affected by the number of
platelets because the bleeding time may also reflects the
platelet numbers.
🔊
6. Ability of the blood vessels to constrict and retract
here in bleeding time we test for primary hemostasis. And 2. Simplate Method
based on the past lesson primary hemostasis involves ● contains a spring-loaded blade within a plastic case
🔊
vasculature,blood vessels, and platelets. which holds a double blade.
the spring makes the method standardized, so
EXAMPLES OF DISEASE/CONDITIONS THAT MAY YIELD the deep of the wound is standardized by the spring
ABNORMAL BLEEDING TIME RESULTS: ● when activated, the blade springs forward from the
Von-Willebrand’s Disease housing and makes a cut on the skin.
Bernard-Soulier Syndrome
🔊
Glanzmann Thrombasthenia
This conditions are under qualitative platelet defects and
these may also affect the platelet bleeding time results.
Other Methods for Bleeding Time:
1. Mielke Method (Template bleeding time)
● a modification of Ivy method
● utilizes a template containing a standardized slit in
place of a disposable lancet
SUBTOPIC
Additional Information
BULLET LEGENDS:
📑
☑ -PowerPoint Presentation
🔊-Module Packet/Neo Notes
- Additional Discussions/.l
BLEEDING TIME
In order to detect qualitative platelet abnormalities, platelet function
tests are designed for patients who are experiencing symptoms of Two methods under Bleeding Time:
mucocutaneous bleeding. Platelet count is an essential laboratory
test to perform before the analysis of platelet function since DUKE METHOD
thrombocytopenia is the common cause of hemorrhage.
Platelet morphology is also noted in cases of Bernard-Soulier ☑first described by Duke in 1912
Syndrome which reveals large gray platelets on the peripheral blood ● involves the use of a lancet to make an incision either on the
smear and thrombocytopenia. Only in the presence of bleeding finger or on the earlobe. A drop of blood is blotted on to the
symptoms and a platelet count that exceeds 50,000/uL is suggestive filter paper every 30 seconds until the blood ceases to flow.
of qualitative platelet disorders. ● This is not a recommended method because it is not precise
or accurate.
Principle: IVY METHOD
☑The bleeding time is the time it takes for a small standardized
wound, introduced into the capillary bed of the finger or ☑modified by Ivy in 1941
earlobe, to stop bleeding. ● involves the use of a blood pressure cuff inflated at 40
This test reflects both platelet number and platelet functional mmHg. In this method, two separate cuts in the forearm 5
integrity. It is dependent upon the elasticity of the skin and capillary cm below the fold of the elbow are made and blood is blotted
vessels, the efficiency of the tissue fluids and the mechanical and on to the filter paper every 30 seconds until the bleeding
chemical action of thrombocytes. stops.
● The length of time required for the bleeding to stop is
recorded as the bleeding time.
, FACTORS AFFECTING BLEEDING TIME: ● a blade is placed in a special handle such that when
🔊
1. Intercapillary pressure the template is placed on the forearm, the blade
Duke method is more affected by intercapillary method would make an incision having a standardized depth
since the procedure in Duke method is not standardized as and length
compared with Ivy method.
🔊
2. Size and depth of the wound
Depending on the age we have the recommended
puncture:
Children & Adults: 2.4mm-3mm
Infants: 1.6mm
3. Efficiency of the tissue fluids in accelerating the clotting
process
🔊
4. Thickness and vascularity of the skin
Avoid heavily callous sites
🔊
5. Chemical and mechanical actions of platelets
Bleeding time may also be affected by the number of
platelets because the bleeding time may also reflects the
platelet numbers.
🔊
6. Ability of the blood vessels to constrict and retract
here in bleeding time we test for primary hemostasis. And 2. Simplate Method
based on the past lesson primary hemostasis involves ● contains a spring-loaded blade within a plastic case
🔊
vasculature,blood vessels, and platelets. which holds a double blade.
the spring makes the method standardized, so
EXAMPLES OF DISEASE/CONDITIONS THAT MAY YIELD the deep of the wound is standardized by the spring
ABNORMAL BLEEDING TIME RESULTS: ● when activated, the blade springs forward from the
Von-Willebrand’s Disease housing and makes a cut on the skin.
Bernard-Soulier Syndrome
🔊
Glanzmann Thrombasthenia
This conditions are under qualitative platelet defects and
these may also affect the platelet bleeding time results.
Other Methods for Bleeding Time:
1. Mielke Method (Template bleeding time)
● a modification of Ivy method
● utilizes a template containing a standardized slit in
place of a disposable lancet
