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Exam (elaborations)

PCB 3063-Test Bank for: Chapter 11: Chromosome Structure and Organelle DNA

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PCB 3063-Test Bank for: Chapter 11: Chromosome Structure and Organelle DNA Multiple-Choice Questions 1. Which of the following is not true of negatively supercoiled DNA? a. Eases the separation of nucleotide strands during replication and transcription. b. Allows DNA to be packed into small spaces. c. Has less than 10 bp per turn of its helix. d. Is more negatively charged due to additional phosphates per turn of the helix. e. Is found in most cells. Answer: c Section: 11.1 Comprehension Question 2. How many complete rotations would most likely correspond to a positively supercoiled DNA molecule that is 100 bp in length? a. 0 b. 5 c. 10 d. 15 e. 100 Answer: d Section: 11.1 Comprehension Question 3. How many complete rotations would most likely correspond to a negatively supercoiled DNA molecule that is 100 bp in length? a. 0 b. 5 c. 10 d. 15 e. 100 Answer: b Section: 11.1 Comprehension Question 4. How many complete rotations would most likely correspond to a relaxed DNA molecule that is 100 bp in length? a. 0 b. 5 c. 10 d. 15 e. 100 Answer: c Section: 11.1 Comprehension Question 5. How many base pairs per turn of the helix would most likely correspond to a relaxed DNA molecule? a. 0 b. 5 c. 10 d. 15 e. 100 Answer: c Section: 11.1 Comprehension Question 6. How many base pairs per turn of the helix would most likely correspond to a positively supercoiled DNA molecule? a. 0 b. 5 c. 10 d. 15 e. 100 Answer: b Section: 11.1 Comprehension Question 7. How many base pairs per turn of the helix would most likely correspond to a negatively supercoiled DNA molecule? a. 0 b. 5 c. 10 d. 15 e. 100 Answer: d Section: 11.1 Comprehension Question 8. Which of the following is not true of bacterial DNA? a. Most bacterial genomes consist of a single circular DNA molecule. b. Bacterial DNA is not attached to any proteins that help to compact it. c. Bacterial DNA is confined to a region in the cell called the nucleoid. d. Many bacteria contain additional DNA in the form of small circular molecules called plasmids. e. About 3 to 4 million base pairs of DNA are found in a typical bacterial genome. Answer: b Section: 11.1 Comprehension Question 9. You are studying a small eukaryotic gene of about 2000 bp in length. Estimate how many copies of histone H4 you would find along this region of the chromosome. a. 10 b. 20 c. 40 d. 80 e. 100 Answer: b Section: 11.1 Comprehension Question 10. You are studying a small eukaryotic gene of about 2000 bp in length. Estimate how many copies of histone H1 you would find along this region of the chromosome. a. 10 b. 20 c. 40 d. 80 e. 100 Answer: a Section: 11.1 Comprehension Question 11. The human Y chromosome is about 50 million base pairs long. About how many nucleosomes would you expect to find associated with this chromosome? a. 2,500 b. 50,000 c. 250,000 d. 1,000,000 e. 50,000,000 Answer: a Section: 11.1 Comprehension Question 12. Which of the following amino acids has a positive charge that helps to hold the DNA in contact with the histones? a. Alanine b. Arginine c. Leucine d. Valine e. Serine Answer: b Section: 11.1 Comprehension Question

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