PHARM FINAL PT 2
1. Betamethasone- Class/MOA
*Answer√√ Corticosteroid
Stimulates production of pulmonary surfactant, stimulates fetal lung maturation
2. Betamethasone- Indication
*Answer√√ Preterm labor (reduces neonatal respiratory distress syndrome), re-duces intracerebral
hemorrhage
3. Betamethasone- Adverse Effects/Specials
*Answer√√ Decreased fetal breathing/movement Monitor fetal HR and blood sugars
4. Clomiphene- Class/MOA
*Answer√√ Ovulatory Stimulant, SERM
Helps hypothalamus release gonadotropin-releasing hormone, leading to elevations in FSH/LG
5. Clomiphene- Indication
*Answer√√ Infertility due to ovulation
6. Clomiphene- Contraindication
,*Answer√√ Pregnancy, ovarian cysts, adrenal/thyroid disorders, abnormal vaginal bleeding
7. Clomiphene- Adverse Effects
*Answer√√ Increased risk of multiple births, vaginal bleeding, pelvic pain, bloat-ing, flushing, and
breast tenderness
8. Clomiphene- Specials
*Answer√√ Can also be used in men to treat andropause
9. Estrogens- MOA
*Answer√√ By itself- inhibit FSH and cause a surge in LH resulting in ovulation
With progesterone (contraceptive)- controls menstrual bleeding while progesterone prevents ovulation
General- female reproductive tract development and maintenance, inhibits bone reabsorption
10. Estrogens- Indication
*Answer√√ Contraception when combined with progesterone, acne, severe
post-menopausal symptoms, ovarian failure, hypogonadism, osteoporosis prophylaxis, dysfunctional uterine bleed-
ing
11. Estrogen- Contraindication
, *Answer√√ Pregnancy, smoking, HTN, heart disease, pre-puberty, breast/estro-
gen-sensitive cancers
12. Estrogen- Adverse Effects
*Answer√√ Increased blood coagulation, endometrial/ovarian/breast cancer
13. Estrogen- Specials
*Answer√√ Discontinue prior to procedures with extended immobility due to increased clotting risk
14. Finasteride- Class/MOA
*Answer√√ BPH Drug
Reduces usable testosterone, reduces prostate size, increases hair growth
15. Finasteride- Indication
*Answer√√ BPH, male pattern baldness
16. Finasteride- Contraindication
*Answer√√ Pregnancy, liver disease, Saw Palmetto
17. Finasteride- Adverse Effects
, *Answer√√ Decreased libido, reduced ejaculate volume, gynecomastia, erectile dysfunction
1. Betamethasone- Class/MOA
*Answer√√ Corticosteroid
Stimulates production of pulmonary surfactant, stimulates fetal lung maturation
2. Betamethasone- Indication
*Answer√√ Preterm labor (reduces neonatal respiratory distress syndrome), re-duces intracerebral
hemorrhage
3. Betamethasone- Adverse Effects/Specials
*Answer√√ Decreased fetal breathing/movement Monitor fetal HR and blood sugars
4. Clomiphene- Class/MOA
*Answer√√ Ovulatory Stimulant, SERM
Helps hypothalamus release gonadotropin-releasing hormone, leading to elevations in FSH/LG
5. Clomiphene- Indication
*Answer√√ Infertility due to ovulation
6. Clomiphene- Contraindication
,*Answer√√ Pregnancy, ovarian cysts, adrenal/thyroid disorders, abnormal vaginal bleeding
7. Clomiphene- Adverse Effects
*Answer√√ Increased risk of multiple births, vaginal bleeding, pelvic pain, bloat-ing, flushing, and
breast tenderness
8. Clomiphene- Specials
*Answer√√ Can also be used in men to treat andropause
9. Estrogens- MOA
*Answer√√ By itself- inhibit FSH and cause a surge in LH resulting in ovulation
With progesterone (contraceptive)- controls menstrual bleeding while progesterone prevents ovulation
General- female reproductive tract development and maintenance, inhibits bone reabsorption
10. Estrogens- Indication
*Answer√√ Contraception when combined with progesterone, acne, severe
post-menopausal symptoms, ovarian failure, hypogonadism, osteoporosis prophylaxis, dysfunctional uterine bleed-
ing
11. Estrogen- Contraindication
, *Answer√√ Pregnancy, smoking, HTN, heart disease, pre-puberty, breast/estro-
gen-sensitive cancers
12. Estrogen- Adverse Effects
*Answer√√ Increased blood coagulation, endometrial/ovarian/breast cancer
13. Estrogen- Specials
*Answer√√ Discontinue prior to procedures with extended immobility due to increased clotting risk
14. Finasteride- Class/MOA
*Answer√√ BPH Drug
Reduces usable testosterone, reduces prostate size, increases hair growth
15. Finasteride- Indication
*Answer√√ BPH, male pattern baldness
16. Finasteride- Contraindication
*Answer√√ Pregnancy, liver disease, Saw Palmetto
17. Finasteride- Adverse Effects
, *Answer√√ Decreased libido, reduced ejaculate volume, gynecomastia, erectile dysfunction
