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DOSAGE CALCULATION EXAM V2 – BSN HESI 215
NIGHTINGALE COLLEGE 2026 EXAM LATEST VERSION
QUESTIONS AND ANSWERS 2026 – 2027 EDITION
DOSAGE CALCULATION EXAM V2 – BSN HESI 215
NIGHTINGALE COLLEGE
250 Multiple Choice Questions with Rationales
SECTION 1: BASIC DOSAGE CALCULATIONS (Questions 1-30)
1. The physician orders amoxicillin 500 mg PO every 8 hours. The medication is
available as 250 mg tablets. How many tablets will the nurse administer per dose?
• A) 0.5 tablet
• B) 2 tablets
• C) 1 tablet
• D) 1.5 tablets
• E) 2.5 tablets
Rationale: Use the formula: Desired / Available × Quantity = 500 mg / 250 mg × 1 tablet
= 2 tablets. Always check that the prescribed dose is within the safe range. The standard
adult dose is 250-500 mg every 8 hours; 2 tablets is the correct answer.
2. A client is prescribed digoxin 0.125 mg PO daily. The medication is available as
0.25 mg scored tablets. How many tablets should the nurse administer?
• A) 1 tablet
• B) 0.5 tablet
• C) 0.25 tablet
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• D) 2 tablets
• E) 0.75 tablet
Rationale: Desired / Available × Quantity = 0.125 mg / 0.25 mg × 1 tablet = 0.5 tablet.
The tablet is scored, so 0.5 tablet can be accurately administered. Digoxin levels must
be monitored; a dose of 0.125 mg is typical for maintenance in older adults.
3. A client is prescribed furosemide 40 mg IV push. Available is 10 mg/mL. How
many mL will the nurse administer?
• A) 2 mL
• B) 6 mL
• C) 4 mL
• D) 8 mL
• E) 10 mL
Rationale: Desired / Available × Quantity = 40 mg / 10 mg/mL = 4 mL. IV push
furosemide should be administered slowly (20 mg/min or 1 minute per 10 mg). The
nurse should administer 4 mL over approximately 2 minutes.
4. A client is prescribed metoprolol 50 mg PO BID. The medication is available as
100 mg tablets. How many tablets will the nurse administer?
• A) 2 tablets
• B) 0.5 tablet
• C) 1 tablet
• D) 0.25 tablet
• E) 0.75 tablet
Rationale: Desired / Available × Quantity = 50 mg / 100 mg × 1 tablet = 0.5 tablet.
Metoprolol is available as scored tablets to allow for accurate splitting. BID means
twice daily.
5. A client is prescribed levothyroxine 0.075 mg PO daily. Available is 75 mcg
tablets. How many tablets should the nurse administer?
• A) 1 tablet
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• B) 0.5 tablet
• C) 1.5 tablets
• D) 0.75 tablet
• E) 2 tablets
Rationale: Convert 0.075 mg to mcg: 0.075 mg × 1000 = 75 mcg. Desired / Available =
75 mcg / 75 mcg = 1 tablet. Levothyroxine requires consistent dosing; 0.075 mg is
equivalent to 75 mcg.
6. A client is prescribed cefazolin 750 mg IV every 8 hours. The vial is labeled 500
mg/2 mL. How many mL will the nurse administer?
• A) 1.5 mL
• B) 3 mL
• C) 4 mL
• D) 2.5 mL
• E) 5 mL
Rationale: Desired / Available × Quantity = 750 mg / 500 mg × 2 mL = 3 mL. Cefazolin
should be infused over 15-30 minutes for IV administration.
7. A client is prescribed clopidogrel 75 mg PO daily. Available is 75 mg tablets. How
many tablets should the nurse administer?
• A) 1 tablet
• B) 0.5 tablet
• C) 2 tablets
• D) 1.5 tablets
• E) 0.75 tablet
Rationale: Desired / Available = 75 mg / 75 mg = 1 tablet. Clopidogrel is a standard dose
for antiplatelet therapy.
8. A client is prescribed prednisone 20 mg PO BID for 5 days. Available is 10 mg
tablets. How many tablets will the nurse administer per dose?
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• A) 1 tablet
• B) 2 tablets
• C) 3 tablets
• D) 0.5 tablet
• E) 1.5 tablets
Rationale: Desired / Available = 20 mg / 10 mg = 2 tablets. Prednisone dosing is often
tapered; the nurse should administer 2 tablets per dose.
9. A client is prescribed enoxaparin 40 mg SC daily. Available is 60 mg/0.6 mL. How
many mL will the nurse administer?
• A) 0.2 mL
• B) 0.6 mL
• C) 1 mL
• D) 0.4 mL
• E) 0.3 mL
Rationale: Desired / Available × Quantity = 40 mg / 60 mg × 0.6 mL = 0.4 mL. Enoxaparin
is administered subcutaneously in the abdomen.
10. A client is prescribed ondansetron 8 mg IV push. Available is 4 mg/2 mL. How
many mL will the nurse administer?
• A) 4 mL
• B) 2 mL
• C) 3 mL
• D) 5 mL
• E) 6 mL
Rationale: Desired / Available × Quantity = 8 mg / 4 mg × 2 mL = 4 mL. Ondansetron IV
push is administered slowly over 2-5 minutes.
11. A client is prescribed potassium chloride 20 mEq PO. Available is 10 mEq/15
mL. How many mL will the nurse administer?
DOSAGE CALCULATION EXAM V2 – BSN HESI 215
NIGHTINGALE COLLEGE 2026 EXAM LATEST VERSION
QUESTIONS AND ANSWERS 2026 – 2027 EDITION
DOSAGE CALCULATION EXAM V2 – BSN HESI 215
NIGHTINGALE COLLEGE
250 Multiple Choice Questions with Rationales
SECTION 1: BASIC DOSAGE CALCULATIONS (Questions 1-30)
1. The physician orders amoxicillin 500 mg PO every 8 hours. The medication is
available as 250 mg tablets. How many tablets will the nurse administer per dose?
• A) 0.5 tablet
• B) 2 tablets
• C) 1 tablet
• D) 1.5 tablets
• E) 2.5 tablets
Rationale: Use the formula: Desired / Available × Quantity = 500 mg / 250 mg × 1 tablet
= 2 tablets. Always check that the prescribed dose is within the safe range. The standard
adult dose is 250-500 mg every 8 hours; 2 tablets is the correct answer.
2. A client is prescribed digoxin 0.125 mg PO daily. The medication is available as
0.25 mg scored tablets. How many tablets should the nurse administer?
• A) 1 tablet
• B) 0.5 tablet
• C) 0.25 tablet
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• D) 2 tablets
• E) 0.75 tablet
Rationale: Desired / Available × Quantity = 0.125 mg / 0.25 mg × 1 tablet = 0.5 tablet.
The tablet is scored, so 0.5 tablet can be accurately administered. Digoxin levels must
be monitored; a dose of 0.125 mg is typical for maintenance in older adults.
3. A client is prescribed furosemide 40 mg IV push. Available is 10 mg/mL. How
many mL will the nurse administer?
• A) 2 mL
• B) 6 mL
• C) 4 mL
• D) 8 mL
• E) 10 mL
Rationale: Desired / Available × Quantity = 40 mg / 10 mg/mL = 4 mL. IV push
furosemide should be administered slowly (20 mg/min or 1 minute per 10 mg). The
nurse should administer 4 mL over approximately 2 minutes.
4. A client is prescribed metoprolol 50 mg PO BID. The medication is available as
100 mg tablets. How many tablets will the nurse administer?
• A) 2 tablets
• B) 0.5 tablet
• C) 1 tablet
• D) 0.25 tablet
• E) 0.75 tablet
Rationale: Desired / Available × Quantity = 50 mg / 100 mg × 1 tablet = 0.5 tablet.
Metoprolol is available as scored tablets to allow for accurate splitting. BID means
twice daily.
5. A client is prescribed levothyroxine 0.075 mg PO daily. Available is 75 mcg
tablets. How many tablets should the nurse administer?
• A) 1 tablet
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• B) 0.5 tablet
• C) 1.5 tablets
• D) 0.75 tablet
• E) 2 tablets
Rationale: Convert 0.075 mg to mcg: 0.075 mg × 1000 = 75 mcg. Desired / Available =
75 mcg / 75 mcg = 1 tablet. Levothyroxine requires consistent dosing; 0.075 mg is
equivalent to 75 mcg.
6. A client is prescribed cefazolin 750 mg IV every 8 hours. The vial is labeled 500
mg/2 mL. How many mL will the nurse administer?
• A) 1.5 mL
• B) 3 mL
• C) 4 mL
• D) 2.5 mL
• E) 5 mL
Rationale: Desired / Available × Quantity = 750 mg / 500 mg × 2 mL = 3 mL. Cefazolin
should be infused over 15-30 minutes for IV administration.
7. A client is prescribed clopidogrel 75 mg PO daily. Available is 75 mg tablets. How
many tablets should the nurse administer?
• A) 1 tablet
• B) 0.5 tablet
• C) 2 tablets
• D) 1.5 tablets
• E) 0.75 tablet
Rationale: Desired / Available = 75 mg / 75 mg = 1 tablet. Clopidogrel is a standard dose
for antiplatelet therapy.
8. A client is prescribed prednisone 20 mg PO BID for 5 days. Available is 10 mg
tablets. How many tablets will the nurse administer per dose?
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• A) 1 tablet
• B) 2 tablets
• C) 3 tablets
• D) 0.5 tablet
• E) 1.5 tablets
Rationale: Desired / Available = 20 mg / 10 mg = 2 tablets. Prednisone dosing is often
tapered; the nurse should administer 2 tablets per dose.
9. A client is prescribed enoxaparin 40 mg SC daily. Available is 60 mg/0.6 mL. How
many mL will the nurse administer?
• A) 0.2 mL
• B) 0.6 mL
• C) 1 mL
• D) 0.4 mL
• E) 0.3 mL
Rationale: Desired / Available × Quantity = 40 mg / 60 mg × 0.6 mL = 0.4 mL. Enoxaparin
is administered subcutaneously in the abdomen.
10. A client is prescribed ondansetron 8 mg IV push. Available is 4 mg/2 mL. How
many mL will the nurse administer?
• A) 4 mL
• B) 2 mL
• C) 3 mL
• D) 5 mL
• E) 6 mL
Rationale: Desired / Available × Quantity = 8 mg / 4 mg × 2 mL = 4 mL. Ondansetron IV
push is administered slowly over 2-5 minutes.
11. A client is prescribed potassium chloride 20 mEq PO. Available is 10 mEq/15
mL. How many mL will the nurse administer?
