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i-Human Dan Jones Case Study: 42-Year-Old Male with Diarrhea Complete History, Physical Exam Findings & Differential Diagnosis (DDx)

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Master your clinical reasoning and ace the simulation screens for the i-Human "Dan Jones" case study featuring a 42-year-old male presenting with acute to subacute diarrhea. This comprehensive document delivers step-by-step guidance through the patient history, targeted physical exam maneuvers, and a fully developed differential diagnosis matrix with clinical rationales. Perfect for nurse practitioner and medical students, it highlights critical indicators to differentiate infectious colitis, Clostridioides difficile, malabsorption, and inflammatory bowel disease (IBD) under current clinical guidelines.

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,DAN JONES
42-Year-Old Male With Acute Diarrhea
Advanced Differential Diagnosis Clinical Case Study



PAGE 1 — CASE SETUP
PATIENT PROFILE

Name: Dan Jones
Age: 42 years
Sex: Male
Height: 5'10" (178 cm)
Weight: 180 lb (81.8 kg)
Setting: Outpatient clinic with laboratory, ECG, and radiographic capabilities
Reason for Encounter: Diarrhea

CHIEF COMPLAINT

“I've been having frequent watery diarrhea for the past several days.”

CLINICAL OBJECTIVE

Evaluate an adult male with acute diarrhea and determine:

• Duration and severity of symptoms
• Degree of dehydration
• Presence of inflammatory or invasive features
• Potential infectious exposures
• Medication-related causes
• Need for laboratory or stool testing
• Appropriate management and follow-up




PAGE 2 — OPENING ENCOUNTER

, Dan arrives at the outpatient clinic independently.

He reports that he has been experiencing frequent loose stools for approximately four days.
Initially, he thought the symptoms would resolve on their own, but the diarrhea has continued.

He states that he has needed to use the bathroom several times each day and has become
increasingly concerned about dehydration.

PATIENT'S INITIAL STATEMENT

“It started a few days ago. At first I thought it was something I ate, but it hasn't really gone
away.”

INITIAL CLINICAL PRIORITIES

The clinician should first establish:

1. When the diarrhea began
2. Number of stools per day
3. Stool consistency
4. Presence of blood or mucus
5. Fever
6. Vomiting
7. Abdominal pain
8. Hydration status
9. Recent travel
10. Food exposure
11. Antibiotic exposure
12. Sick contacts




PAGE 3 — HISTORY OF PRESENT
ILLNESS
Dan reports that the diarrhea began approximately four days ago.

During the first day, he experienced approximately three loose stools. The frequency increased
over the following two days.

He now reports approximately five to seven watery bowel movements per day.

The stool is predominantly watery without obvious gross blood.

Document information

Uploaded on
August 19, 2026
Number of pages
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Written in
2026/2027
Type
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