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SHARP ESO 2026/2027 ACTUAL EXAM 300 ACTUAL QUESTIONS AND CORRECT ANSWERS WITH RATIONALE LATEST UPDATE

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Prepare for success on the Sharp HealthCare Emergency Standing Orders (ESO) Exam with this comprehensive study guide featuring 300 authentic practice questions with detailed rationales covering all essential emergency nursing protocols and algorithms. This essential resource covers every critical exam domain including cardiac arrest algorithms (PEA, V-Fib, Asystole, V-Tach), symptomatic bradycardia and hypotension management with Atropine, Dopamine, Epinephrine, and transcutaneous pacing, respiratory distress interventions with oxygen delivery, Albuterol for bronchospasm, and Non-Invasive Ventilation, anaphylaxis treatment with Epinephrine 0.3mg IM, Diphenhydramine, Hydrocortisone, and Famotidine, status epilepticus management with Ativan 2mg IVP and lateral decubitus positioning, opioid and benzodiazepine reversal with Narcan and Romazicon with specific dosing protocols (Narcan 0.1mg IVP q1min max 0.4mg for RR10; Romazicon 0.2mg IVP over 15 seconds max 0.6mg), sepsis screening with SIRS criteria and lactate/culture acquisition, increased intracranial pressure protocols with HOB elevation to 30 degrees and hyperventilation to CO2 26-30, chest pain management with MONA (Morphine 2mg IVP q5min max 10mg, Oxygen, Nitroglycerin 0.4mg SL x2, Aspirin 325mg), unstable V-tach with synchronized cardioversion at 200 joules and Versed 0.5mg IVP sedation (max 1mg), V-Fib/Pulseless V-Tach algorithm with Amiodarone 300mg IVP followed by 150mg, Epinephrine 1mg IVP q3-5min, and defibrillation, Rapid Response Team activation, ETCO2 monitoring, therapeutic hypothermia 32-36°C, H's and T's for reversible causes, medication administration routes including IV, IO, and ET routes with 2-2.5x dosing, and proper documentation requirements. Each question is carefully crafted to reflect actual exam formats with multiple-choice options, correct answers, and in-depth rationales explaining the underlying emergency medicine principles, medication dosing, and clinical decision-making. Whether you are preparing for your Sharp ESO certification exam, emergency department orientation, or advancing your career in emergency nursing, this guide provides the rigorous practice and knowledge reinforcement needed to excel. Ideal for Sharp Healthcare nurses, emergency department RNs, and all healthcare professionals seeking ESO competency, this comprehensive question bank ensures you are fully prepared for the culminating assessment of your Emergency Standing Orders training.

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SHARP ESO 2026/2027 ACTUAL EXAM 300 ACTUAL
QUESTIONS AND CORRECT ANSWERS WITH
RATIONALE LATEST UPDATE

1. What is the initial treatment for a patient in Asystole?
A) Defibrillation
B) CPR for 2 minutes, O2 at 15 L/min via Ambu bag, Epinephrine 1 mg IVP/IO
C) Transcutaneous pacing
D) Amiodarone 300 mg IVP
Answer B: CPR for 2 minutes, O2 at 15 L/min via Ambu bag, Epinephrine 1
mg IVP/IO
Rationale: Asystole is treated with high-quality CPR, oxygenation, and
Epinephrine. Defibrillation and pacing are not recommended.




2. How often should Epinephrine be repeated in pulseless cardiac arrest?
A) Every 1 minute
B) Every 3–5 minutes
C) Every 10 minutes
D) Only once
Answer B: Every 3–5 minutes
Rationale: Epinephrine 1 mg IVP/IO should be repeated every 3–5 minutes during
pulseless arrest.

,3. What is the initial Epinephrine dose for pulseless arrhythmias?
A) 0.5 mg IVP
B) 0.1 mg IVP
C) 1 mg IVP/IO (0.1 mg/mL)
D) 2 mg IVP
Answer C: 1 mg IVP/IO (0.1 mg/mL)
Rationale: The standard dose is 1 mg IVP/IO, using the 0.1 mg/mL concentration.




4. What is the recommended dose of Epinephrine when administered via
endotracheal tube (ETT)?
A) 0.5 mg diluted in 5 mL NS
B) 2–2.5 times the IV dose diluted in 10 mL NS
C) Same as IV dose
D) 5 mg diluted in 20 mL NS
Answer B: 2–2.5 times the IV dose diluted in 10 mL NS
Rationale: ETT doses are 2–2.5 times the IV dose, diluted in 10 mL normal saline.




5. What is Pulseless Electrical Activity (PEA)?
A) Absence of all electrical activity
B) Presence of electrical activity that fails to generate a detectable pulse
C) Ventricular fibrillation

,D) Wide complex tachycardia with a pulse
Answer B: Presence of electrical activity that fails to generate a detectable
pulse
Rationale: PEA is defined as organized electrical activity without a palpable pulse.




6. What is the initial treatment for PEA?
A) Defibrillation
B) CPR for 2 minutes, O2 at 15 L/min via Ambu bag, Epinephrine 1 mg IVP/IO
C) Amiodarone 300 mg IVP
D) Transcutaneous pacing
Answer B: CPR for 2 minutes, O2 at 15 L/min via Ambu bag, Epinephrine 1
mg IVP/IO
Rationale: PEA is treated with CPR, oxygenation, and Epinephrine. Defibrillation is
not indicated.




7. What are the "Hs" in the reversible causes of PEA?
A) Hypovolemia, Hypoxia, Hydrogen ion (acidosis), Hypo/hyperkalemia,
Hypoglycemia, Hypothermia
B) Hypovolemia, Hypoxia, Hydrogen ion, Hypo/hyperkalemia, Hypoglycemia,
Hypothermia
C) Heart block, Hypertension, Hyperthermia
D) Hypovolemia, Hypothermia, Hyperglycemia

, Answer B: Hypovolemia, Hypoxia, Hydrogen ion, Hypo/hyperkalemia,
Hypoglycemia, Hypothermia
Rationale: The Hs are Hypovolemia, Hypoxia, Hydrogen ion (acidosis),
Hypo/hyperkalemia, Hypoglycemia, and Hypothermia.




8. What are the "Ts" in the reversible causes of PEA?
A) Tachycardia, Tamponade, Thrombosis
B) Toxins, Tamponade, Thrombosis, Trauma, Tension pneumothorax
C) Thrombosis, Trauma, Temperature
D) Toxins, Tachycardia, Thrombosis
Answer B: Toxins, Tamponade, Thrombosis, Trauma, Tension pneumothorax
Rationale: The Ts are Toxins, Tamponade, Thrombosis, Trauma, and Tension
pneumothorax.




9. What should be done if hypovolemia is suspected during PEA treatment?
A) Administer Epinephrine 2 mg
B) Infuse 250 mL NS bolus; repeat in 5 minutes if no improvement
C) Start Norepinephrine
D) Administer Amiodarone
Answer B: Infuse 250 mL NS bolus; repeat in 5 minutes if no improvement
Rationale: If hypovolemia is known or suspected, a 250 mL NS bolus should be
given. Repeat in 5 minutes if no clinical improvement.

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