NCLEX:v n Neurov n Pharmacology
1. Alpha-1vnreceptors:vn-vnFoundvninvnvascularvnsmoothvnmuscle
- Peripheralvnvasoconstriction
- Increasevn systemicvn vascularvn resistancevn (SVR)
2. Beta-1vnreceptors:vn-vnFoundvninvnheartvnandvnintestinalvnsmoothvnmuscle
- Increasevn contractility
- IncreasevnSV,vnHR,vnandvnCO
3. Beta-2vnreceptor:vn -vnFoundvninvnbronchialvnvasculature
- Bronchodilation
- Coronaryvnarteryvnvasodilation
4. Namev n somev n Alphav n Adrenergicv n Agonists.:v n Epinephrine,vnNorepinephrine,vnEphedrine,vnPhen
yle-phrine
5. WhatvnarevnthevnindicationsvnforvnAlphavnAdrenergicvnAgonists?:vnCardiacvnarrest,vnshoc
k,vnhypotension,vncontrollingvnbleeding,vnanaphylaxis,vnnasalvndecongestion
6. WhatvnisvnthevnactionvnofvnAlphavnAdrenergicvnAgonists?:vnActivationvnofvna-
receptorsvnofvnthevnSNSvnleadingvntovnvasoconstrictionvnandvnpupilvnconstriction
7. WhatvnarevnsomevnadversevneffectsvnofvnAlphavnAdrenergicvnAgonists?:vnHypertensi
on,vntachycardia,vnangina,vnhyperglycemia,vnnecrosisvn(extravasation)
8. WhichvndrugsvncanvninteractvnwithvnAlphavnAdrenergicvnAgonists?:vnMAOIs,vnTCAs,vnAlpha/B
etavnblockers
9. WhatvnarevnthevnlocalvneffectsvnofvnEphedrinevnandvnPhenylephrine?:vnVasoconstrictionvnwh
envnusedvninvnnasalvnsprays
10. NamevnsomevnAlphavnAdrenergicvnAntagonists:vnPrazosin,vnDoxazosin,vnTerazosin,vnTamsulosin
,vnAlfuzosin,vnSilodosin,vnPhentolamine
11. WhatvnarevnthevnindicationsvnforvnAlphavnAdrenergicvnAntagonists?:vnHypertensionvn(HT
N),vnBenignvnProstaticvnHyperplasiavn(BPH),vnRaynaud'svndisease,vnPheochromocytoma
12. WhatvnisvnthevnactionvnofvnAlphavnAdrenergicvnAntagonists?:vnBlocksvnactivationvnofvnalpha-
recep-torsvninvnthevnSympatheticvnNervousvnSystemvn(SNS)vnleadingvntovnvasodilationvnandvndecreasedvnbloodvnpressure.
13. WhatvnarevnsomevnadversevneffectsvnofvnAlphavnAdrenergicvnAntagonists?:vnHypotensio
n,vnreflexvntachycardia,vnnasalvncongestion
14. WhatvnisvnavnnursingvnconsiderationvnforvnAlphavnAdrenergicvnAntagonists?:vnFirstvndos
ev n mayvncausevnorthostaticvnhypotension,vnsovnpatientsvnshouldvnstayvninvnbed.vnNotvnsafevnforvnusevninvnchildren,vnpregnancy
,vnorvnbreastfeeding.
, NCLEX:v n Neurov n Pharmacology
15. NamevnsomevnBetavnAdrenergicvnAgonists.:vnEpinephrine,vnNE,vnDopamine,vnDobutamine,vnIsop
ro-terenol,vnAlbuterol
16. WhatvnarevnthevnindicationsvnforvnBetavnAdrenergicvnAgonists?:vnAVvnblock,vnCardiacvnarre
st,vnshock,vnHR,vnasthma,vnpretermvnlabor
17. WhatvnisvnthevnactionvnofvnBetavnAdrenergicvnAgonists?:vnActivatesvnbetavnreceptorsvn(SNSvnstim
ula-tion)vnthatvnresultsvninvnincreasedvnHRvn(b-1),vnbronchodilation,vnandvnuterinevnrelaxationvn(b-2)
18. WhatvnarevnsomevnadversevneffectsvnofvnBetavnAdrenergicvnAgonists?:vnTachydysrhythmia
s,vnangina,vnhyperglycemia,vnnecrosisvn(extravasation)
19. Whatv n arev n somev n drugv n interactionsv n tov n considerv n withv n Betav n Adrenergi
cv n Ago-nists?:vnMAOIs,vnTCAs,vnBBs
20. Namevnsomevnnon-selectivevnbeta-
antagonists.:vnPropranolol,vnnadolol,vnpindolol,vnsotalol,vntimo-lol
21. Whatvnarevnthevnindicationsvnforvnnon-selectivevnbeta-
antagonists?:vnHypertension,vnangi-na,vndysrhythmias,vnmyocardialvninfarction
22. Whatvnisvnthevnactionvnofvnnon-selectivevnbeta-
antagonists?:vnBlockingvnactivationvnofvnbothvnbeta-1vnandvnbeta-
2vnreceptorsvnleadingvntovndecreasedvnheartvnrate,vnforcevnofvncontraction,vnsuppressionvnofvnimpulsevnconductionvnthroughvnAVvn
nodevn(beta-1),vnbronchoconstriction,vnandvndecreasedvngluconeogenesisvn(beta-2)
23. Whatv n arev n somev n nursingv n considerationsv n forv n non-selectivev n beta-
antagonists?-
:vnAvoidvninvnpatientsvnwithvnsinusvnbradycardiavnorvnAVvnblock,vncautionvninvnheartvnfailurevnpatientsvn(duevntovndecreasedvncardia
cvnoutput),vnbevncautiousvnwithvnasthmavnpatientsvn(duevntovnpotentialvnbronchoconstriction),vnmonitorvnforvnhypoglycemiavninv
ndiabeticvn patients,vntapervnottvntovnavoidvnreboundvncardiacvnexcitation,vnusevnwithvncautionvninvnpatientsvnwithvnmentalvnhealthv
nconditions
24. Whyv n shouldv n cautionv n bev n exercisedv n inv n clientsv n withv n life-
threateningv n allergiesvnwhenvnonvnavn(non-selective)vnbeta-
blocker?:vnEpinephrinevnmayvnbevnlessvnettectivevninvnpatientsvnonvnbeta-blockers
25. NamevnsomevnselectivevnBetavnantagonists.:vnmetoprolol,vnacebutolol,vnatenolol,vnbetaxolol,vnbisopr
o-lol,vnesmolol,vncarvedilol,vnlabetalol
26. WhatvnarevnthevnindicationsvnforvnselectivevnBetavnantagonists?:vnHRN,vnangina,vnHF,vnMI
27. WhatvnisvnthevnactionvnofvnselectivevnBetavnantagonists?:vnBlocksvnactivationvnofvnb-1vnreceptorsvn’
decreasevnHR,vnforcevnofvncontraction,vnsuppressionvnofvnimpulsevnconductionvnthroughvnAVvnnodevn(dec.vnCO)
1. Alpha-1vnreceptors:vn-vnFoundvninvnvascularvnsmoothvnmuscle
- Peripheralvnvasoconstriction
- Increasevn systemicvn vascularvn resistancevn (SVR)
2. Beta-1vnreceptors:vn-vnFoundvninvnheartvnandvnintestinalvnsmoothvnmuscle
- Increasevn contractility
- IncreasevnSV,vnHR,vnandvnCO
3. Beta-2vnreceptor:vn -vnFoundvninvnbronchialvnvasculature
- Bronchodilation
- Coronaryvnarteryvnvasodilation
4. Namev n somev n Alphav n Adrenergicv n Agonists.:v n Epinephrine,vnNorepinephrine,vnEphedrine,vnPhen
yle-phrine
5. WhatvnarevnthevnindicationsvnforvnAlphavnAdrenergicvnAgonists?:vnCardiacvnarrest,vnshoc
k,vnhypotension,vncontrollingvnbleeding,vnanaphylaxis,vnnasalvndecongestion
6. WhatvnisvnthevnactionvnofvnAlphavnAdrenergicvnAgonists?:vnActivationvnofvna-
receptorsvnofvnthevnSNSvnleadingvntovnvasoconstrictionvnandvnpupilvnconstriction
7. WhatvnarevnsomevnadversevneffectsvnofvnAlphavnAdrenergicvnAgonists?:vnHypertensi
on,vntachycardia,vnangina,vnhyperglycemia,vnnecrosisvn(extravasation)
8. WhichvndrugsvncanvninteractvnwithvnAlphavnAdrenergicvnAgonists?:vnMAOIs,vnTCAs,vnAlpha/B
etavnblockers
9. WhatvnarevnthevnlocalvneffectsvnofvnEphedrinevnandvnPhenylephrine?:vnVasoconstrictionvnwh
envnusedvninvnnasalvnsprays
10. NamevnsomevnAlphavnAdrenergicvnAntagonists:vnPrazosin,vnDoxazosin,vnTerazosin,vnTamsulosin
,vnAlfuzosin,vnSilodosin,vnPhentolamine
11. WhatvnarevnthevnindicationsvnforvnAlphavnAdrenergicvnAntagonists?:vnHypertensionvn(HT
N),vnBenignvnProstaticvnHyperplasiavn(BPH),vnRaynaud'svndisease,vnPheochromocytoma
12. WhatvnisvnthevnactionvnofvnAlphavnAdrenergicvnAntagonists?:vnBlocksvnactivationvnofvnalpha-
recep-torsvninvnthevnSympatheticvnNervousvnSystemvn(SNS)vnleadingvntovnvasodilationvnandvndecreasedvnbloodvnpressure.
13. WhatvnarevnsomevnadversevneffectsvnofvnAlphavnAdrenergicvnAntagonists?:vnHypotensio
n,vnreflexvntachycardia,vnnasalvncongestion
14. WhatvnisvnavnnursingvnconsiderationvnforvnAlphavnAdrenergicvnAntagonists?:vnFirstvndos
ev n mayvncausevnorthostaticvnhypotension,vnsovnpatientsvnshouldvnstayvninvnbed.vnNotvnsafevnforvnusevninvnchildren,vnpregnancy
,vnorvnbreastfeeding.
, NCLEX:v n Neurov n Pharmacology
15. NamevnsomevnBetavnAdrenergicvnAgonists.:vnEpinephrine,vnNE,vnDopamine,vnDobutamine,vnIsop
ro-terenol,vnAlbuterol
16. WhatvnarevnthevnindicationsvnforvnBetavnAdrenergicvnAgonists?:vnAVvnblock,vnCardiacvnarre
st,vnshock,vnHR,vnasthma,vnpretermvnlabor
17. WhatvnisvnthevnactionvnofvnBetavnAdrenergicvnAgonists?:vnActivatesvnbetavnreceptorsvn(SNSvnstim
ula-tion)vnthatvnresultsvninvnincreasedvnHRvn(b-1),vnbronchodilation,vnandvnuterinevnrelaxationvn(b-2)
18. WhatvnarevnsomevnadversevneffectsvnofvnBetavnAdrenergicvnAgonists?:vnTachydysrhythmia
s,vnangina,vnhyperglycemia,vnnecrosisvn(extravasation)
19. Whatv n arev n somev n drugv n interactionsv n tov n considerv n withv n Betav n Adrenergi
cv n Ago-nists?:vnMAOIs,vnTCAs,vnBBs
20. Namevnsomevnnon-selectivevnbeta-
antagonists.:vnPropranolol,vnnadolol,vnpindolol,vnsotalol,vntimo-lol
21. Whatvnarevnthevnindicationsvnforvnnon-selectivevnbeta-
antagonists?:vnHypertension,vnangi-na,vndysrhythmias,vnmyocardialvninfarction
22. Whatvnisvnthevnactionvnofvnnon-selectivevnbeta-
antagonists?:vnBlockingvnactivationvnofvnbothvnbeta-1vnandvnbeta-
2vnreceptorsvnleadingvntovndecreasedvnheartvnrate,vnforcevnofvncontraction,vnsuppressionvnofvnimpulsevnconductionvnthroughvnAVvn
nodevn(beta-1),vnbronchoconstriction,vnandvndecreasedvngluconeogenesisvn(beta-2)
23. Whatv n arev n somev n nursingv n considerationsv n forv n non-selectivev n beta-
antagonists?-
:vnAvoidvninvnpatientsvnwithvnsinusvnbradycardiavnorvnAVvnblock,vncautionvninvnheartvnfailurevnpatientsvn(duevntovndecreasedvncardia
cvnoutput),vnbevncautiousvnwithvnasthmavnpatientsvn(duevntovnpotentialvnbronchoconstriction),vnmonitorvnforvnhypoglycemiavninv
ndiabeticvn patients,vntapervnottvntovnavoidvnreboundvncardiacvnexcitation,vnusevnwithvncautionvninvnpatientsvnwithvnmentalvnhealthv
nconditions
24. Whyv n shouldv n cautionv n bev n exercisedv n inv n clientsv n withv n life-
threateningv n allergiesvnwhenvnonvnavn(non-selective)vnbeta-
blocker?:vnEpinephrinevnmayvnbevnlessvnettectivevninvnpatientsvnonvnbeta-blockers
25. NamevnsomevnselectivevnBetavnantagonists.:vnmetoprolol,vnacebutolol,vnatenolol,vnbetaxolol,vnbisopr
o-lol,vnesmolol,vncarvedilol,vnlabetalol
26. WhatvnarevnthevnindicationsvnforvnselectivevnBetavnantagonists?:vnHRN,vnangina,vnHF,vnMI
27. WhatvnisvnthevnactionvnofvnselectivevnBetavnantagonists?:vnBlocksvnactivationvnofvnb-1vnreceptorsvn’
decreasevnHR,vnforcevnofvncontraction,vnsuppressionvnofvnimpulsevnconductionvnthroughvnAVvnnodevn(dec.vnCO)
