PharmacologyvnExamvn1vnNCLEXvnQuestions
Whichvncomponentsvnofvnpharmacokineticsvndoesvnthevnnursevnneedvntovnunde
rstandvnbeforevnadministeringvnavndrug?vn(Selectvnallvnthatvnapply.)
a.vnDrugsvnwithvnavnsmallervnvolumevnofvndrugvndistributionvnhavevnavnlongervnh
alf-life.
b.vnOralvndrugsvnarevndissolvedvnthroughvnthevnprocessvnofvnpinocytosis.
c.vnPatientsvnwithvnkidneyvndiseasevnmayvnhavevnfewervnprotein-
bindingvnsitesvnandvnarevnatvnriskvnforvndrugvntoxicity.
d.vnRapidvnabsorptionvndecreasesvnthevnbioavailabilityvnofvnthevndrug.
e.vnWhenvnthevndrugvnmetabolismvnratevnisvndecreased,vnexcessvndrugvnaccumu
lationvncanvnoccur,vnwhichvncanvncausevntoxicity.vn-vncorrectvnanswer✔ ✔
C,E
Thevnnursevnwillvnquestionvnthevnhealthvncarevnprovidervnifvnavndrugvnwithvnavnha
lf-
lifevn(vntvn½)vnofvnmorevnthanvn24vnhoursvnisvnorderedvntovnbevngivenvnmorevnthanv
nhowvnoften?
,a.vnOncevndaily
b.vnEveryvnothervnday
c.vnTwicevnweekly
d.vnOncevnweeklyvn-vncorrectvnanswer✔ ✔ A
Thevnnursevnisvnexplainingvndrugvnactionvntovnavnnursingvnstudent.vnWhichvnstat
ementvnmadevnbyvnthevnnursevnisvncorrect?
a.vnWater-solublevnandvnionizedvndrugsvnarevnquicklyvnabsorbed.
b.vnAvndrugvnnotvnboundvntovnproteinvnisvnanvnactivevndrug.
c.vnMostvnreceptorsvnarevnfoundvnundervnthevncellvnmembrane.
d.vnToxicvneffectsvncanvnresultvnifvnthevntroughvnlevelvnisvnlow.vn-
vncorrectvnanswer✔ ✔ B
,AvnNativevnAmericanvnpatientvnisvnnewlyvndiagnosedvnwithvntypevn2vndiabetesv
nmellitusvnandvnisvnprescribed vnthevnantidiabeticvndrug vnmetformin vn500vnmgvn
pervnosvnwithvnmorningvnandvneveningvnmeals.vnWhichvnstatementvnbestvnindic
atesvntovnthevnnursevnthatvnthevnpatientvnwillvnadherevntovnthevntherapeuticvnregi
men?
a.vnIvnwillvnnovnlongervnputvnsugarvnonvnmyvncerealvnbecausevnthatvnwillvnhelpvnm
evnbevnhealthier.
b.vnIfvnIvntakevnthisvnmedicine,vnIvnwillvnfeelvnbettervnsoonvnandvnwon'tvnhavevntovn
takevnitvnanymore.
c.vnTovnreducevnthevnpossibilityvnofvndamagevntovnmyvnbody,vnIvnmustvntakevnthev
nmedicinevnasvnscheduled.
d.vnIvnhavevndiabetesvnbecausevnofvnmyvnancestry,vnsovnthere'svnnotvnmuchvnIvnca
nvndovnaboutvnit.vn-vncorrectvnanswer✔ ✔ A
Thevnnursevnisvnawarevnthatvnthevnratevnofvnabsorptionvncanvnbevnchangedvnbyvnw
hichvnactions?vn(Selectvnallvnthatvnapply.)
a.vnModifyingvngastricvnemptyingvntime
b.vnChangingvngastricvnpH
, c.vnDecreasingvninflammation
d.vnFormingvndrugvncomplexes
e.vnEatingvntoovnslowlyvn-vncorrectvnanswer✔ ✔ A,B,D
Thevnnursevnisvnreviewingvnavnpatient'svnmedicationsvnasvnpartvnofvnpatientvntea
ching.vnThevnnursevnisvnawarevnthatvnwhichvndrugvnisvnleastvnlikelyvntovncausevnp
hotosensitivity?
a.vnPenicillins
b.vnSulfonamides
c.vnSulfonylureas
d.vnThiazidesvn-vncorrectvnanswer✔ ✔ A
Thevnnursevnisvnmeetingvnwithvnavncommunityvngroupvnaboutvnmedicationvnsaf
ety.vnThevnnursevnmustvnemphasizevnthatvnpatientsvnatvnhighvnriskvnforvndrugvnin
teractionsvnincludevnwhichvngroups?vn(Selectvnallvnthatvnapply.)
Whichvncomponentsvnofvnpharmacokineticsvndoesvnthevnnursevnneedvntovnunde
rstandvnbeforevnadministeringvnavndrug?vn(Selectvnallvnthatvnapply.)
a.vnDrugsvnwithvnavnsmallervnvolumevnofvndrugvndistributionvnhavevnavnlongervnh
alf-life.
b.vnOralvndrugsvnarevndissolvedvnthroughvnthevnprocessvnofvnpinocytosis.
c.vnPatientsvnwithvnkidneyvndiseasevnmayvnhavevnfewervnprotein-
bindingvnsitesvnandvnarevnatvnriskvnforvndrugvntoxicity.
d.vnRapidvnabsorptionvndecreasesvnthevnbioavailabilityvnofvnthevndrug.
e.vnWhenvnthevndrugvnmetabolismvnratevnisvndecreased,vnexcessvndrugvnaccumu
lationvncanvnoccur,vnwhichvncanvncausevntoxicity.vn-vncorrectvnanswer✔ ✔
C,E
Thevnnursevnwillvnquestionvnthevnhealthvncarevnprovidervnifvnavndrugvnwithvnavnha
lf-
lifevn(vntvn½)vnofvnmorevnthanvn24vnhoursvnisvnorderedvntovnbevngivenvnmorevnthanv
nhowvnoften?
,a.vnOncevndaily
b.vnEveryvnothervnday
c.vnTwicevnweekly
d.vnOncevnweeklyvn-vncorrectvnanswer✔ ✔ A
Thevnnursevnisvnexplainingvndrugvnactionvntovnavnnursingvnstudent.vnWhichvnstat
ementvnmadevnbyvnthevnnursevnisvncorrect?
a.vnWater-solublevnandvnionizedvndrugsvnarevnquicklyvnabsorbed.
b.vnAvndrugvnnotvnboundvntovnproteinvnisvnanvnactivevndrug.
c.vnMostvnreceptorsvnarevnfoundvnundervnthevncellvnmembrane.
d.vnToxicvneffectsvncanvnresultvnifvnthevntroughvnlevelvnisvnlow.vn-
vncorrectvnanswer✔ ✔ B
,AvnNativevnAmericanvnpatientvnisvnnewlyvndiagnosedvnwithvntypevn2vndiabetesv
nmellitusvnandvnisvnprescribed vnthevnantidiabeticvndrug vnmetformin vn500vnmgvn
pervnosvnwithvnmorningvnandvneveningvnmeals.vnWhichvnstatementvnbestvnindic
atesvntovnthevnnursevnthatvnthevnpatientvnwillvnadherevntovnthevntherapeuticvnregi
men?
a.vnIvnwillvnnovnlongervnputvnsugarvnonvnmyvncerealvnbecausevnthatvnwillvnhelpvnm
evnbevnhealthier.
b.vnIfvnIvntakevnthisvnmedicine,vnIvnwillvnfeelvnbettervnsoonvnandvnwon'tvnhavevntovn
takevnitvnanymore.
c.vnTovnreducevnthevnpossibilityvnofvndamagevntovnmyvnbody,vnIvnmustvntakevnthev
nmedicinevnasvnscheduled.
d.vnIvnhavevndiabetesvnbecausevnofvnmyvnancestry,vnsovnthere'svnnotvnmuchvnIvnca
nvndovnaboutvnit.vn-vncorrectvnanswer✔ ✔ A
Thevnnursevnisvnawarevnthatvnthevnratevnofvnabsorptionvncanvnbevnchangedvnbyvnw
hichvnactions?vn(Selectvnallvnthatvnapply.)
a.vnModifyingvngastricvnemptyingvntime
b.vnChangingvngastricvnpH
, c.vnDecreasingvninflammation
d.vnFormingvndrugvncomplexes
e.vnEatingvntoovnslowlyvn-vncorrectvnanswer✔ ✔ A,B,D
Thevnnursevnisvnreviewingvnavnpatient'svnmedicationsvnasvnpartvnofvnpatientvntea
ching.vnThevnnursevnisvnawarevnthatvnwhichvndrugvnisvnleastvnlikelyvntovncausevnp
hotosensitivity?
a.vnPenicillins
b.vnSulfonamides
c.vnSulfonylureas
d.vnThiazidesvn-vncorrectvnanswer✔ ✔ A
Thevnnursevnisvnmeetingvnwithvnavncommunityvngroupvnaboutvnmedicationvnsaf
ety.vnThevnnursevnmustvnemphasizevnthatvnpatientsvnatvnhighvnriskvnforvndrugvnin
teractionsvnincludevnwhichvngroups?vn(Selectvnallvnthatvnapply.)
