RODAKS HEMATOLOGY QUESTIONS
AND ANSWERS
16.bYoubrequirebyourblaboratorybstaffbtobannuallybperformbmanualblupusbanticoag
ulantbprofilesbonbabsetbofbplasmasbwithbknownbvalues.bThisbexercisebisbknownb
as:b
a.bAssaybvalidationbb.bProficiencybtestingbc.bExternalbqualitybassessmentbd.bPre-
pre-analyticalbvariablebassayb-bb.bProficiencybtesting
15.bWhenbperformingbabreceiverboperatingbcurvebanalysis,bwhatb
parameterbassessesbtheboverallbefficacybofbanbassay
a.bAreabunderbthebcurvebb.bPerformanceblimitb(threshold)bc.bPositivebpredictiveb
valuebd.bNegativebpredictivebvalueb-ba.bAreabunderbthebcurve
14.bReviewbofblaboratorybreportbintegritybisbanbexamplebof:ba.bPreanalyticalbqual
itybassuranceb
b.bAnalyticalbqualitybcontrolbc.bPostanalyticalbqualitybassurancebd.bExternalbqualit
ybassuranceb-bc.bPostanalyticalbqualitybassurance
13.bRegularbreviewbofbbloodbspecimenbcollectionbqualitybisbanbexamplebof:b
a.bPostanalyticalbqualitybassurancebb.bPreanalyticalbqualitybassurancebc.bAnalytic
albqualitybcontrolbd.bExternalbqualitybassuranceb-
bb.bPreanalyticalbqualitybassurance
12.bWhatbagencybprovidesbcontinuingbmedicalblaboratorybeducation?b
a.bColoradobAssociationbforbContinuingbMedicalbLaboratorybEducationb(CACMLE)
b
b.bClinicalbLaboratorybImprovementbAdvisorybCommitteeb(CLIAC)b
c.bCentersbforbMedicarebandbMedicaidbServicesb(CMS)bd.bCollegebofbAmericanb
Pathologistsb(CAP)b-
ba.bColoradobAssociationbforbContinuingbMedicalbLaboratorybEducationb(CACMLE
)
11.bWhatbagencybprovidesbexternalbqualitybassuranceb(proficiency)bsurveysbandbl
aboratorybaccreditation?
ba.bClinicalbLaboratorybImprovementbAdvisorybCommitteeb(CLIAC)b
b.bCentersbforbMedicarebandbMedicaidbServicesb(CMS)bc.bCollegebofbAmericanb
Pathologistsb(CAP)b
d.bJointbCommissionb-bc.bCollegebofbAmericanbPathologistsb(CAP
10.bYoubperformbabclinicalbefficacybtestbandbgetbthebfollowingbresults:b
,Unaffectedbbyb
DiseaseborbConditionb
AffectedbbybDiseaseborbConditionb
Assaybisbnegativeb
40
AffectedbbybDiseaseborbConditionb
Assaybosbnegative
5
Unaffectedbbyb
DiseaseborbCondition
Assaybisbpositiveb
10
AffectedbbybDiseaseborbCondition
Assaybisbpositive
45
Whatbisbthebnumberbofbfalse-negativebresults?ba.b40b
b.b10b
c.b5bd.b45b-bc.b5
9.bYoubpurchasebabpreservedbwholebbloodbspecimenbfrombabdistributorbwhobpro
videsbthebmeanbvaluesbforbseveralbcompletebbloodbcountbanalytes.bWhatbisbthis
bspecimenbcalled?ba.bNormalbspecimenb.bCalibratorb
c.bControlb
d.bBlankb-bc.bControl
ab.bConfirmingblinearitybbb.bSettingbthebreferencebintervalb8.bAblaboratorybscienti
stbmeasuresbprothrombinbtimebforbplasmabaliquotsbfromb15bhealthybmalesbandb
15bhealthybfemalesb.bShebcomputesbthebmeanbandb95.5b
%bconfidencebintervalbandbnotesbthatbtheybduplicatebthebmanufacturer'sbstatistics
bwithinb5b
%b.bThisbprocedurebisbknownbasb:bcb.bDeterminingbthebtherapeuticbrangebdb.b
Establishingbthebreferencebintervalbbybtransferenceb-
bdb.bEstablishingbthebreferencebintervalbbybtransference
7.bTheblaboratorybpurchasesbreagentsbfrombabmanufacturerbandbdevelopsbanbas
saybusingbstandardbreferencesb.bWhatbFDAbcategorybisbthisbassayb?
bab.bClearedbbb.bHomeb-bbrewbcb.bResearchbusebonlybdb.bAnalyteb-
bspecificbreagentb-bdb.bAnalyteb-bspecificbreagent
6.bThebabilitybofbanbassaybtobdistinguishbthebtargetedbanalytebfrombinterferingbs
ubstancesbwithinbthebspecimenbmatrixbisbcalledb:bab.bAnalyticalbspecificitybbb.bA
nalyticalbsensitivitybcb.bClinicalbspecificitybdb.bClinicalbsensitivityb-
bab.bAnalyticalbspecificity
, 5.bAbWBCbcountbcontrolbhasbabmeanbvaluebofb6000b/
bmLbandbabstandardbdeviationbofb300b/bmLb.bWhatbisbtheb95.5b
%bconfidencebintervalb?
bab.b3000btob9000b/
bmLbbb.b5400btob6600b/
bmLbcb.b5500btob6500b/bmLbdb.b5700btob6300b/bmLb-
bbb.b5400btob6600b/bmL
4.bThebacceptablebhemoglobinbcontrolbvaluebrangebisb13b6b0.4bgb/
bdLb.bThebcontrolbisbassayedbfivebtimesbandbproducesbthebfollowingbfivebresults
b:b12.0bgb/
bdLb12.3bgb/
bdLb12.0bgb/
bdLb12.2bgb/
bdLb12.1bgbdLbThesebresultsbareb:bab.bAccuratebbutbnotbprecisebbb.bPreciseb
butbnotbaccuratebcb.bBothbaccuratebandbprecisebdb.bNeitherbaccuratebnorbpreci
seb-bbb.bPrecisebbutbnotbaccurate
3.bWhichbisbabstatisticalbtestbcomparingbmeansb?
bab.bBlandbAltmanbbb.bStudent'sbtbtestbcbANOVAbdb.bPearsonb-
bbb.bStudent'sbtb-btest
Standardbprecautionsbapplybtoballbofbthebfollowingbexceptb
ab.bBloodbb.bCerebrospinalbfluidbcbSemenbdbConcentratedb-
bdbConcentratedbacids
2.bThebmostbimportantbpracticebinbpreventingbthebspreadbofbdiseasebis
babWearingbmasksbduringbpatientbcontactbbb.bProperbhandbwashingbcbWearing
bdisposableblaboratorybcoatsbdbIdentifyingbspecimensbfrombknownborbsuspectedb
HIVbandbHBVbinfectedbpatientsbwithbabredblabelb-bbbProperbhandbwashing
3.bThebappropriatebdilutionbofbbleachbtobbebusedbinblaboratorybdisinfectionbisb:b
a.1b:b2bbb.b1b:b5bc.b1:10bdb1b100b-bcb1:10
4.bHowbfrequentlybshouldbfirebalarmsbandbsprinklerbsystemsbbebtested
ab.bWeeklybbb.bMonthlybcb.bQuarterlybdb.bAnnuallyb-bcb.bQuarterly
5.bWherebshouldbalcoholbandbotherbflammablebchemicalsbbebstoredb?b
ab.bInbanbapprovedbsafetybcanborbstoragebcabinetbawaybfrombheatbsourcesbbb
Underbabhoodbandbarrangedbalphabeticallybforbeasebofbidentificationbinbanbemer
gencybcbInbabrefrigeratorbatb28bCbtob88bCbtobreducebvolatilizationbdb.bOnbabl
owbshelfbinbanbareabprotectedbfromblightb-
bab.bInbanbapprovedbsafetybcanborbstoragebcabinetbawaybfrombheatbsources
6.bThebmostbfrequentbcausebofbneedlebpuncturesbisb:b
AND ANSWERS
16.bYoubrequirebyourblaboratorybstaffbtobannuallybperformbmanualblupusbanticoag
ulantbprofilesbonbabsetbofbplasmasbwithbknownbvalues.bThisbexercisebisbknownb
as:b
a.bAssaybvalidationbb.bProficiencybtestingbc.bExternalbqualitybassessmentbd.bPre-
pre-analyticalbvariablebassayb-bb.bProficiencybtesting
15.bWhenbperformingbabreceiverboperatingbcurvebanalysis,bwhatb
parameterbassessesbtheboverallbefficacybofbanbassay
a.bAreabunderbthebcurvebb.bPerformanceblimitb(threshold)bc.bPositivebpredictiveb
valuebd.bNegativebpredictivebvalueb-ba.bAreabunderbthebcurve
14.bReviewbofblaboratorybreportbintegritybisbanbexamplebof:ba.bPreanalyticalbqual
itybassuranceb
b.bAnalyticalbqualitybcontrolbc.bPostanalyticalbqualitybassurancebd.bExternalbqualit
ybassuranceb-bc.bPostanalyticalbqualitybassurance
13.bRegularbreviewbofbbloodbspecimenbcollectionbqualitybisbanbexamplebof:b
a.bPostanalyticalbqualitybassurancebb.bPreanalyticalbqualitybassurancebc.bAnalytic
albqualitybcontrolbd.bExternalbqualitybassuranceb-
bb.bPreanalyticalbqualitybassurance
12.bWhatbagencybprovidesbcontinuingbmedicalblaboratorybeducation?b
a.bColoradobAssociationbforbContinuingbMedicalbLaboratorybEducationb(CACMLE)
b
b.bClinicalbLaboratorybImprovementbAdvisorybCommitteeb(CLIAC)b
c.bCentersbforbMedicarebandbMedicaidbServicesb(CMS)bd.bCollegebofbAmericanb
Pathologistsb(CAP)b-
ba.bColoradobAssociationbforbContinuingbMedicalbLaboratorybEducationb(CACMLE
)
11.bWhatbagencybprovidesbexternalbqualitybassuranceb(proficiency)bsurveysbandbl
aboratorybaccreditation?
ba.bClinicalbLaboratorybImprovementbAdvisorybCommitteeb(CLIAC)b
b.bCentersbforbMedicarebandbMedicaidbServicesb(CMS)bc.bCollegebofbAmericanb
Pathologistsb(CAP)b
d.bJointbCommissionb-bc.bCollegebofbAmericanbPathologistsb(CAP
10.bYoubperformbabclinicalbefficacybtestbandbgetbthebfollowingbresults:b
,Unaffectedbbyb
DiseaseborbConditionb
AffectedbbybDiseaseborbConditionb
Assaybisbnegativeb
40
AffectedbbybDiseaseborbConditionb
Assaybosbnegative
5
Unaffectedbbyb
DiseaseborbCondition
Assaybisbpositiveb
10
AffectedbbybDiseaseborbCondition
Assaybisbpositive
45
Whatbisbthebnumberbofbfalse-negativebresults?ba.b40b
b.b10b
c.b5bd.b45b-bc.b5
9.bYoubpurchasebabpreservedbwholebbloodbspecimenbfrombabdistributorbwhobpro
videsbthebmeanbvaluesbforbseveralbcompletebbloodbcountbanalytes.bWhatbisbthis
bspecimenbcalled?ba.bNormalbspecimenb.bCalibratorb
c.bControlb
d.bBlankb-bc.bControl
ab.bConfirmingblinearitybbb.bSettingbthebreferencebintervalb8.bAblaboratorybscienti
stbmeasuresbprothrombinbtimebforbplasmabaliquotsbfromb15bhealthybmalesbandb
15bhealthybfemalesb.bShebcomputesbthebmeanbandb95.5b
%bconfidencebintervalbandbnotesbthatbtheybduplicatebthebmanufacturer'sbstatistics
bwithinb5b
%b.bThisbprocedurebisbknownbasb:bcb.bDeterminingbthebtherapeuticbrangebdb.b
Establishingbthebreferencebintervalbbybtransferenceb-
bdb.bEstablishingbthebreferencebintervalbbybtransference
7.bTheblaboratorybpurchasesbreagentsbfrombabmanufacturerbandbdevelopsbanbas
saybusingbstandardbreferencesb.bWhatbFDAbcategorybisbthisbassayb?
bab.bClearedbbb.bHomeb-bbrewbcb.bResearchbusebonlybdb.bAnalyteb-
bspecificbreagentb-bdb.bAnalyteb-bspecificbreagent
6.bThebabilitybofbanbassaybtobdistinguishbthebtargetedbanalytebfrombinterferingbs
ubstancesbwithinbthebspecimenbmatrixbisbcalledb:bab.bAnalyticalbspecificitybbb.bA
nalyticalbsensitivitybcb.bClinicalbspecificitybdb.bClinicalbsensitivityb-
bab.bAnalyticalbspecificity
, 5.bAbWBCbcountbcontrolbhasbabmeanbvaluebofb6000b/
bmLbandbabstandardbdeviationbofb300b/bmLb.bWhatbisbtheb95.5b
%bconfidencebintervalb?
bab.b3000btob9000b/
bmLbbb.b5400btob6600b/
bmLbcb.b5500btob6500b/bmLbdb.b5700btob6300b/bmLb-
bbb.b5400btob6600b/bmL
4.bThebacceptablebhemoglobinbcontrolbvaluebrangebisb13b6b0.4bgb/
bdLb.bThebcontrolbisbassayedbfivebtimesbandbproducesbthebfollowingbfivebresults
b:b12.0bgb/
bdLb12.3bgb/
bdLb12.0bgb/
bdLb12.2bgb/
bdLb12.1bgbdLbThesebresultsbareb:bab.bAccuratebbutbnotbprecisebbb.bPreciseb
butbnotbaccuratebcb.bBothbaccuratebandbprecisebdb.bNeitherbaccuratebnorbpreci
seb-bbb.bPrecisebbutbnotbaccurate
3.bWhichbisbabstatisticalbtestbcomparingbmeansb?
bab.bBlandbAltmanbbb.bStudent'sbtbtestbcbANOVAbdb.bPearsonb-
bbb.bStudent'sbtb-btest
Standardbprecautionsbapplybtoballbofbthebfollowingbexceptb
ab.bBloodbb.bCerebrospinalbfluidbcbSemenbdbConcentratedb-
bdbConcentratedbacids
2.bThebmostbimportantbpracticebinbpreventingbthebspreadbofbdiseasebis
babWearingbmasksbduringbpatientbcontactbbb.bProperbhandbwashingbcbWearing
bdisposableblaboratorybcoatsbdbIdentifyingbspecimensbfrombknownborbsuspectedb
HIVbandbHBVbinfectedbpatientsbwithbabredblabelb-bbbProperbhandbwashing
3.bThebappropriatebdilutionbofbbleachbtobbebusedbinblaboratorybdisinfectionbisb:b
a.1b:b2bbb.b1b:b5bc.b1:10bdb1b100b-bcb1:10
4.bHowbfrequentlybshouldbfirebalarmsbandbsprinklerbsystemsbbebtested
ab.bWeeklybbb.bMonthlybcb.bQuarterlybdb.bAnnuallyb-bcb.bQuarterly
5.bWherebshouldbalcoholbandbotherbflammablebchemicalsbbebstoredb?b
ab.bInbanbapprovedbsafetybcanborbstoragebcabinetbawaybfrombheatbsourcesbbb
Underbabhoodbandbarrangedbalphabeticallybforbeasebofbidentificationbinbanbemer
gencybcbInbabrefrigeratorbatb28bCbtob88bCbtobreducebvolatilizationbdb.bOnbabl
owbshelfbinbanbareabprotectedbfromblightb-
bab.bInbanbapprovedbsafetybcanborbstoragebcabinetbawaybfrombheatbsources
6.bThebmostbfrequentbcausebofbneedlebpuncturesbisb:b