Q&A (Latest 2026/2027 Update) – 100+ Complete Exam Questions
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Coverage of Pharmacokinetics, Pharmacodynamics, Autonomic
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, 1 PHARMACOKINETICS
Which phase of pharmacokinetics involves the movement of a drug from the
site of administration into the bloodstream?
A. Distribution
B. Metabolism
C. Absorption
D. Excretion
Correct answer: Absorption
Rationale: Absorption is the process by which a drug enters systemic
circulation. It is influenced by route, formulation, and blood flow.
#2 PHARMACOKINETICS
First-pass metabolism primarily occurs in which organ?
A. Kidney
B. Liver
C. Lungs
D. Heart
Correct answer: Liver
Rationale: The liver is the primary site of first-pass metabolism, where drugs
are metabolized before reaching systemic circulation.
#3 PHARMACOKINETICS
Which pharmacokinetic parameter reflects the volume of fluid needed to
dissolve the total amount of drug at the same concentration as plasma?
A. Clearance
B. Half-life
C. Volume of distribution
D. Bioavailability
Correct answer: Volume of distribution
Rationale: Volume of distribution (Vd) relates the amount of drug in the
body to the plasma concentration. It helps predict drug distribution into
tissues.
#4 PHARMACOKINETICS
Which phase of pharmacokinetics involves the movement of a drug from the
site of administration into the bloodstream?
A. Distribution
B. Metabolism
C. Absorption