Page 1 of 24
I-HUMAN CASES EXAM: HEENT & PREVENTIVE/PRIMARY
CARE EXAM 2026 QUESTIONS LATEST VERSION
QUESTIONS AND ANSWERS
i-Human Cases Exam: HEENT & Preventive/Primary Care
70 Questions with Detailed Rationales
Based on Common i-Human Virtual Simulation Scenarios
PART 1: HEENT – EYE COMPLAINTS (Questions 1-14)
Question 1
A 35-year-old female presents with a 2-day history of sudden-onset floaters and flashes
of light in her left eye, followed by a dark curtain descending over her vision. She denies
eye pain. What is the most likely diagnosis?
A) Posterior vitreous detachment
B) Retinal detachment
C) Migraine with aura
D) Optic neuritis
Answer: B
Rationale: Retinal detachment typically presents with sudden-onset floaters, flashes of light
(photopsia), and a dark curtain descending over the visual field. It is a painless emergency
requiring immediate ophthalmology referral. Posterior vitreous detachment also presents with
floaters but typically does not cause a visual field defect.
Question 2
What is the most appropriate initial intervention for a patient with suspected retinal
detachment?
A) Immediate ophthalmology referral
B) CT scan of the head
C) Eye drops
D) Observation
, Page 2 of 24
Answer: A
Rationale: Retinal detachment is an emergency requiring immediate ophthalmology referral.
Time is critical to preserve vision. The patient should be instructed to keep the head still and
avoid strenuous activity.
Question 3
A 70-year-old male presents with gradual, painless loss of peripheral vision and
difficulty seeing at night. He reports trouble reading and driving. What is the most
likely diagnosis?
A) Macular degeneration
B) Cataracts
C) Glaucoma
D) Diabetic retinopathy
Answer: C
Rationale: Glaucoma is characterized by gradual, painless loss of peripheral vision and
difficulty with night vision. It is often asymptomatic until advanced stages. Risk factors
include age >60, African American race, and family history. Cup-to-disc ratio >0.5 on
fundoscopy is suggestive.
Question 4
What is the most appropriate diagnostic test for glaucoma?
A) Tonometry
B) Fundoscopy
C) Visual field testing
D) All of the above
Answer: D
Rationale: Tonometry measures intraocular pressure (IOP). Fundoscopy assesses the optic
nerve for cupping. Visual field testing detects peripheral vision loss. All three are important
for diagnosing and monitoring glaucoma.
Question 5
What is the most appropriate treatment for open-angle glaucoma?
A) Prostaglandin analogs (e.g., latanoprost)
B) Beta-blockers (e.g., timolol)
, Page 3 of 24
C) Laser trabeculoplasty
D) All of the above may be indicated
Answer: D
Rationale: Prostaglandin analogs (latanoprost), beta-blockers (timolol), and laser
trabeculoplasty are all treatment options for open-angle glaucoma. The goal is to reduce
intraocular pressure and prevent optic nerve damage.
Question 6
What is the most important education for a patient with glaucoma?
A) "Take medications as prescribed."
B) "Attend regular eye exams."
C) "Report any vision changes."
D) All of the above
Answer: D
Rationale: Education includes medication adherence, regular eye exams, and reporting
vision changes. Glaucoma is a chronic condition requiring lifelong management.
Question 7
A 65-year-old female presents with a painless, gradual loss of central vision in both eyes.
She reports difficulty reading and recognizing faces. What is the most likely diagnosis?
A) Macular degeneration
B) Cataracts
C) Glaucoma
D) Diabetic retinopathy
Answer: A
Rationale: Macular degeneration is characterized by painless, gradual loss of central vision.
Risk factors include age >60, smoking, and family history. Dry AMD is more common; wet
AMD is more severe.
Question 8
What is the most important risk factor for macular degeneration?
A) Smoking
B) Age
I-HUMAN CASES EXAM: HEENT & PREVENTIVE/PRIMARY
CARE EXAM 2026 QUESTIONS LATEST VERSION
QUESTIONS AND ANSWERS
i-Human Cases Exam: HEENT & Preventive/Primary Care
70 Questions with Detailed Rationales
Based on Common i-Human Virtual Simulation Scenarios
PART 1: HEENT – EYE COMPLAINTS (Questions 1-14)
Question 1
A 35-year-old female presents with a 2-day history of sudden-onset floaters and flashes
of light in her left eye, followed by a dark curtain descending over her vision. She denies
eye pain. What is the most likely diagnosis?
A) Posterior vitreous detachment
B) Retinal detachment
C) Migraine with aura
D) Optic neuritis
Answer: B
Rationale: Retinal detachment typically presents with sudden-onset floaters, flashes of light
(photopsia), and a dark curtain descending over the visual field. It is a painless emergency
requiring immediate ophthalmology referral. Posterior vitreous detachment also presents with
floaters but typically does not cause a visual field defect.
Question 2
What is the most appropriate initial intervention for a patient with suspected retinal
detachment?
A) Immediate ophthalmology referral
B) CT scan of the head
C) Eye drops
D) Observation
, Page 2 of 24
Answer: A
Rationale: Retinal detachment is an emergency requiring immediate ophthalmology referral.
Time is critical to preserve vision. The patient should be instructed to keep the head still and
avoid strenuous activity.
Question 3
A 70-year-old male presents with gradual, painless loss of peripheral vision and
difficulty seeing at night. He reports trouble reading and driving. What is the most
likely diagnosis?
A) Macular degeneration
B) Cataracts
C) Glaucoma
D) Diabetic retinopathy
Answer: C
Rationale: Glaucoma is characterized by gradual, painless loss of peripheral vision and
difficulty with night vision. It is often asymptomatic until advanced stages. Risk factors
include age >60, African American race, and family history. Cup-to-disc ratio >0.5 on
fundoscopy is suggestive.
Question 4
What is the most appropriate diagnostic test for glaucoma?
A) Tonometry
B) Fundoscopy
C) Visual field testing
D) All of the above
Answer: D
Rationale: Tonometry measures intraocular pressure (IOP). Fundoscopy assesses the optic
nerve for cupping. Visual field testing detects peripheral vision loss. All three are important
for diagnosing and monitoring glaucoma.
Question 5
What is the most appropriate treatment for open-angle glaucoma?
A) Prostaglandin analogs (e.g., latanoprost)
B) Beta-blockers (e.g., timolol)
, Page 3 of 24
C) Laser trabeculoplasty
D) All of the above may be indicated
Answer: D
Rationale: Prostaglandin analogs (latanoprost), beta-blockers (timolol), and laser
trabeculoplasty are all treatment options for open-angle glaucoma. The goal is to reduce
intraocular pressure and prevent optic nerve damage.
Question 6
What is the most important education for a patient with glaucoma?
A) "Take medications as prescribed."
B) "Attend regular eye exams."
C) "Report any vision changes."
D) All of the above
Answer: D
Rationale: Education includes medication adherence, regular eye exams, and reporting
vision changes. Glaucoma is a chronic condition requiring lifelong management.
Question 7
A 65-year-old female presents with a painless, gradual loss of central vision in both eyes.
She reports difficulty reading and recognizing faces. What is the most likely diagnosis?
A) Macular degeneration
B) Cataracts
C) Glaucoma
D) Diabetic retinopathy
Answer: A
Rationale: Macular degeneration is characterized by painless, gradual loss of central vision.
Risk factors include age >60, smoking, and family history. Dry AMD is more common; wet
AMD is more severe.
Question 8
What is the most important risk factor for macular degeneration?
A) Smoking
B) Age