BIOD 152 ANATOMY & PHYSIOLOGY II - PORTAGE
LEARNING MODULE 6 EXAM (REPRODUCTIVE SYSTEM)
| 2026 VERIFIED QUESTIONS & ANSWERS | GRADED A+
202 Questions with Answers and Detailed Rationales
100 PERCENT GUARANTEED PASS
INSTANT DOWNLOAD ANSWERS INCLUDED
IMPORTANCE OF THIS DOCUMENT
This comprehensive examination preparation guide has been meticulously developed to help you succeed in the
BIOD 152 ANATOMY & PHYSIOLOGY II - PORTAGE LEARNING MODULE 6 EXAM (REPRODUCTIVE
SYSTEM) | 2026 VERIFIED QUESTIONS & ANSWERS | GRADED A+. It contains 202 carefully selected
questions that reflect the most current exam content and testing strategies. Each question is accompanied by a
correct answer and a detailed rationale that explains the underlying pathophysiology, pharmacology, or clinical
reasoning.
Self-Assessment – Test your knowledge and Exam Preparation – Familiarize yourself with the
identify areas requiring further question format and content
study areas
Concept Reinforcement – Deepen your Confidence Building – Develop test-taking
understanding through strategies and reduce
evidence-based exam anxiety
rationales
Time Management – Practice answering
questions under simulated
exam conditions
Review Summary 202 Questions
Foundations - Application - BIOD 152 Anatomy & Physiology II Portage Learning Module 6 Reproductive
System 2026 & A Anatomy & Physiology II Reproductive System Undergraduate YEAR 3 / Graduate
All answers with rationales
,Table of Contents
Content Area Questions Key Topics
BIOD 152 Anatomy & 1-34 Likely, Phase, Explains, Primary, Mechanism
Physiology II Portage
Learning Module 6
Reproductive System 2026 &
A Anatomy & Physiology II
Reproductive System
Undergraduate YEAR 3 /
Graduate
Likely 35-68 Phase, Researcher, Hormonal, Directly, Cells
Phase 69-102 Explains, Cycle, Ovarian, Sperm, Describes
Cycle 103-136 Explains, Surge, Cells, Primary, Serum
Directly 137-170 Cycle, Change, Enzyme, Event, Phase
Hormonal 171-202 Likely, Researcher, Phase, Mechanism, Cycle
TOTAL 202 All questions include answers and detailed rationales
,Section A - BIOD 152 Anatomy & Physiology II Portage
Learning Module 6 Reproductive System 2026 & A Anatomy
& Physiology II Reproductive System Undergraduate YEAR
3 / Graduate
Q1.
A compound that selectively inhibits the enzyme aromatase is administered to an adult
male. Which of the following direct hormonal changes is most expected?
A. Decreased serum estradiol and increased B. Decreased serum estradiol and
serum testosterone decreased serum testosterone
C. Increased serum estradiol and increased D. Increased serum estradiol and decreased
serum testosterone serum testosterone
Correct: A - Decreased serum estradiol and increased serum testosterone
Rationale:Aromatase converts testosterone to estradiol. Inhibiting it reduces estradiol
production, leading to less negative feedback on the hypothalamus/pituitary, which increases
GnRH and LH, stimulating more testosterone synthesis. Thus, estradiol falls while
testosterone rises. Other options reflect incorrect feedback or conversion effects.
Q2.
In a nonpregnant female with regular menstrual cycles, a surge of LH triggers ovulation.
Which of the following best explains the molecular mechanism by which the LH surge
induces follicular rupture?
A. LH directly stimulates smooth muscle B. LH activates matrix metalloproteinases
contraction in the follicular wall and prostaglandin synthesis, weakening the
follicular wall
C. LH causes a rapid decrease in D. LH promotes proliferation of granulosa
intrafollicular pressure leading to collapse cells, increasing follicular volume
Correct: B - LH activates matrix metalloproteinases and prostaglandin synthesis,
weakening the follicular wall
Rationale:The LH surge triggers a cascade involving prostaglandins, cytokines, and matrix
metalloproteinases that degrade collagen in the follicular wall, leading to rupture. Direct
smooth muscle contraction (A) is not a primary mechanism; pressure changes (C) are not the
cause; proliferation (D) occurs earlier but does not cause rupture.
Page 3
, Section A - BIOD 152 Anatomy & Physiology II Portage Learning Module 6 Reproductive System 2026 & A Anatomy & Physiology II
Reproductive System Undergraduate YEAR 3 / Graduate
Q3.
A researcher is studying the effects of a novel drug that blocks the action of anti-Müllerian
hormone (AMH). In a male embryo, which of the following developmental outcomes is
most likely?
A. Regression of the paramesonephric duct, B. Persistence of the paramesonephric duct,
normal male internal genitalia development of fallopian tubes and uterus
C. Atrophy of the mesonephric duct, D. Hyperplasia of Leydig cells, increased
absence of epididymis and vas deferens testosterone production
Correct: B - Persistence of the paramesonephric duct, development of fallopian tubes and
uterus
Rationale:AMH causes regression of the paramesonephric (Müllerian) duct in males.
Blocking AMH leads to persistence of the duct, which differentiates into fallopian tubes,
uterus, and upper vagina. The mesonephric duct derivatives (epididymis, vas deferens) are
stimulated by testosterone, not AMH, so they would still develop; Leydig cell hyperplasia is
unrelated.
Q4.
During the proliferative phase of the menstrual cycle, the endometrium thickens primarily
due to which of the following mechanisms?
A. Progesterone-induced stromal edema B. Estrogen-stimulated proliferation of
and glandular secretion endometrial glands and stroma
C. LH-induced angiogenesis and leukocyte D. FSH-stimulated glycogen deposition in
infiltration the endometrium
Correct: B - Estrogen-stimulated proliferation of endometrial glands and stroma
Rationale:The proliferative phase is driven by estrogen from the developing follicles, which
stimulates mitotic activity in endometrial glands and stroma, thickening the endometrium.
Progesterone (A) dominates the secretory phase; LH (C) does not directly affect
endometrium; FSH (D) acts on ovarian follicles, not endometrium.
Q5.
A 45-year-old man presents with infertility. Semen analysis reveals normal sperm count
and motility, but a low semen volume. Which of the following is the most likely cause?
A. Obstruction of the ejaculatory duct B. Hypogonadotropic hypogonadism
C. Impaired function of the seminal vesicles D. Sertoli cell-only syndrome
Correct: C - Impaired function of the seminal vesicles
Page 4
LEARNING MODULE 6 EXAM (REPRODUCTIVE SYSTEM)
| 2026 VERIFIED QUESTIONS & ANSWERS | GRADED A+
202 Questions with Answers and Detailed Rationales
100 PERCENT GUARANTEED PASS
INSTANT DOWNLOAD ANSWERS INCLUDED
IMPORTANCE OF THIS DOCUMENT
This comprehensive examination preparation guide has been meticulously developed to help you succeed in the
BIOD 152 ANATOMY & PHYSIOLOGY II - PORTAGE LEARNING MODULE 6 EXAM (REPRODUCTIVE
SYSTEM) | 2026 VERIFIED QUESTIONS & ANSWERS | GRADED A+. It contains 202 carefully selected
questions that reflect the most current exam content and testing strategies. Each question is accompanied by a
correct answer and a detailed rationale that explains the underlying pathophysiology, pharmacology, or clinical
reasoning.
Self-Assessment – Test your knowledge and Exam Preparation – Familiarize yourself with the
identify areas requiring further question format and content
study areas
Concept Reinforcement – Deepen your Confidence Building – Develop test-taking
understanding through strategies and reduce
evidence-based exam anxiety
rationales
Time Management – Practice answering
questions under simulated
exam conditions
Review Summary 202 Questions
Foundations - Application - BIOD 152 Anatomy & Physiology II Portage Learning Module 6 Reproductive
System 2026 & A Anatomy & Physiology II Reproductive System Undergraduate YEAR 3 / Graduate
All answers with rationales
,Table of Contents
Content Area Questions Key Topics
BIOD 152 Anatomy & 1-34 Likely, Phase, Explains, Primary, Mechanism
Physiology II Portage
Learning Module 6
Reproductive System 2026 &
A Anatomy & Physiology II
Reproductive System
Undergraduate YEAR 3 /
Graduate
Likely 35-68 Phase, Researcher, Hormonal, Directly, Cells
Phase 69-102 Explains, Cycle, Ovarian, Sperm, Describes
Cycle 103-136 Explains, Surge, Cells, Primary, Serum
Directly 137-170 Cycle, Change, Enzyme, Event, Phase
Hormonal 171-202 Likely, Researcher, Phase, Mechanism, Cycle
TOTAL 202 All questions include answers and detailed rationales
,Section A - BIOD 152 Anatomy & Physiology II Portage
Learning Module 6 Reproductive System 2026 & A Anatomy
& Physiology II Reproductive System Undergraduate YEAR
3 / Graduate
Q1.
A compound that selectively inhibits the enzyme aromatase is administered to an adult
male. Which of the following direct hormonal changes is most expected?
A. Decreased serum estradiol and increased B. Decreased serum estradiol and
serum testosterone decreased serum testosterone
C. Increased serum estradiol and increased D. Increased serum estradiol and decreased
serum testosterone serum testosterone
Correct: A - Decreased serum estradiol and increased serum testosterone
Rationale:Aromatase converts testosterone to estradiol. Inhibiting it reduces estradiol
production, leading to less negative feedback on the hypothalamus/pituitary, which increases
GnRH and LH, stimulating more testosterone synthesis. Thus, estradiol falls while
testosterone rises. Other options reflect incorrect feedback or conversion effects.
Q2.
In a nonpregnant female with regular menstrual cycles, a surge of LH triggers ovulation.
Which of the following best explains the molecular mechanism by which the LH surge
induces follicular rupture?
A. LH directly stimulates smooth muscle B. LH activates matrix metalloproteinases
contraction in the follicular wall and prostaglandin synthesis, weakening the
follicular wall
C. LH causes a rapid decrease in D. LH promotes proliferation of granulosa
intrafollicular pressure leading to collapse cells, increasing follicular volume
Correct: B - LH activates matrix metalloproteinases and prostaglandin synthesis,
weakening the follicular wall
Rationale:The LH surge triggers a cascade involving prostaglandins, cytokines, and matrix
metalloproteinases that degrade collagen in the follicular wall, leading to rupture. Direct
smooth muscle contraction (A) is not a primary mechanism; pressure changes (C) are not the
cause; proliferation (D) occurs earlier but does not cause rupture.
Page 3
, Section A - BIOD 152 Anatomy & Physiology II Portage Learning Module 6 Reproductive System 2026 & A Anatomy & Physiology II
Reproductive System Undergraduate YEAR 3 / Graduate
Q3.
A researcher is studying the effects of a novel drug that blocks the action of anti-Müllerian
hormone (AMH). In a male embryo, which of the following developmental outcomes is
most likely?
A. Regression of the paramesonephric duct, B. Persistence of the paramesonephric duct,
normal male internal genitalia development of fallopian tubes and uterus
C. Atrophy of the mesonephric duct, D. Hyperplasia of Leydig cells, increased
absence of epididymis and vas deferens testosterone production
Correct: B - Persistence of the paramesonephric duct, development of fallopian tubes and
uterus
Rationale:AMH causes regression of the paramesonephric (Müllerian) duct in males.
Blocking AMH leads to persistence of the duct, which differentiates into fallopian tubes,
uterus, and upper vagina. The mesonephric duct derivatives (epididymis, vas deferens) are
stimulated by testosterone, not AMH, so they would still develop; Leydig cell hyperplasia is
unrelated.
Q4.
During the proliferative phase of the menstrual cycle, the endometrium thickens primarily
due to which of the following mechanisms?
A. Progesterone-induced stromal edema B. Estrogen-stimulated proliferation of
and glandular secretion endometrial glands and stroma
C. LH-induced angiogenesis and leukocyte D. FSH-stimulated glycogen deposition in
infiltration the endometrium
Correct: B - Estrogen-stimulated proliferation of endometrial glands and stroma
Rationale:The proliferative phase is driven by estrogen from the developing follicles, which
stimulates mitotic activity in endometrial glands and stroma, thickening the endometrium.
Progesterone (A) dominates the secretory phase; LH (C) does not directly affect
endometrium; FSH (D) acts on ovarian follicles, not endometrium.
Q5.
A 45-year-old man presents with infertility. Semen analysis reveals normal sperm count
and motility, but a low semen volume. Which of the following is the most likely cause?
A. Obstruction of the ejaculatory duct B. Hypogonadotropic hypogonadism
C. Impaired function of the seminal vesicles D. Sertoli cell-only syndrome
Correct: C - Impaired function of the seminal vesicles
Page 4
