1. intimal tear
Choose an answer
aorta blood supply 2 most common cause of aortic dissection
in what portion of the aorta are aging
3 berry aneurysm 4
changes most prominent?
1/8
, Terms in this set (54)
aorta blood supply 1. blood supply to the media and adventitia of the aorta provided by vasa
vasorum superior to the renal arteries
2. inferior to renal arteries, the aorta receives O₂ via diffusion of the blood it
is carrying
aorta histo 1. intma: superficial layer w/ endothelia → subendothelial space → internal
elastic lamina
2. media: lamellae of elastic fibers and SMCs; ECM consists of collagen, PGs,
and GAGs
3. adventitia: loose network of collagen and fibroblasts
SMC and fibroblast synth of fibers 1. includes elastin, collagen, and reticulin
2. highly regulated by fibrillin-1, which is activated by TGF-β
age-related changes in aorta 1. high turbulence → SMC apoptosis → fragmentation and calcification of
elastic fibers, fibrosis, and ↑ground substance
2. aging → dilation, lengthening, and tortuous turns of aorta
3. aging changes MOST PROMINENT in the THORACIC AORTA, especially in
pt's w/ HTN
in what portion of the aorta are aging changes most 1. thoracic aorta
prominent? 2. compounded in pt's w/ HTN
aortic aneurysm definition 1. localized pathologic dilation of a blood vessel due to weakening of vessel
wall
2. >50% increase in diameter
normal aorta diameters 1. ascending aorta: 3 cm
2. aortic arch: 2.5 cm
3. descending and abdominal aorta: 1.8-2 cm
classification of aneurysms 1. true saccular
2. true fusiform
3. false
2/8
Choose an answer
aorta blood supply 2 most common cause of aortic dissection
in what portion of the aorta are aging
3 berry aneurysm 4
changes most prominent?
1/8
, Terms in this set (54)
aorta blood supply 1. blood supply to the media and adventitia of the aorta provided by vasa
vasorum superior to the renal arteries
2. inferior to renal arteries, the aorta receives O₂ via diffusion of the blood it
is carrying
aorta histo 1. intma: superficial layer w/ endothelia → subendothelial space → internal
elastic lamina
2. media: lamellae of elastic fibers and SMCs; ECM consists of collagen, PGs,
and GAGs
3. adventitia: loose network of collagen and fibroblasts
SMC and fibroblast synth of fibers 1. includes elastin, collagen, and reticulin
2. highly regulated by fibrillin-1, which is activated by TGF-β
age-related changes in aorta 1. high turbulence → SMC apoptosis → fragmentation and calcification of
elastic fibers, fibrosis, and ↑ground substance
2. aging → dilation, lengthening, and tortuous turns of aorta
3. aging changes MOST PROMINENT in the THORACIC AORTA, especially in
pt's w/ HTN
in what portion of the aorta are aging changes most 1. thoracic aorta
prominent? 2. compounded in pt's w/ HTN
aortic aneurysm definition 1. localized pathologic dilation of a blood vessel due to weakening of vessel
wall
2. >50% increase in diameter
normal aorta diameters 1. ascending aorta: 3 cm
2. aortic arch: 2.5 cm
3. descending and abdominal aorta: 1.8-2 cm
classification of aneurysms 1. true saccular
2. true fusiform
3. false
2/8
