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HESI A2 ENTRANCE ACTUAL EXAM 2026 – 2027
LATEST VERSION QUESTIONS AND ANSWERS
2026 EDITION
HESI A2 Entrance Exam — 250 Practice Questions with Rationales
SECTION 1: READING COMPREHENSION (Questions 1-45)
Passage 1: Telemedicine
Telemedicine refers to the use of digital communication technologies, such as
computers and mobile devices, to provide healthcare services remotely. This practice
allows patients to consult with healthcare providers via video conferencing, secure
messaging, or remote monitoring without needing an in-person office visit.
Telemedicine has expanded rapidly, particularly during the COVID-19 pandemic, as it
reduces exposure risk and increases access to care for individuals in rural or
underserved areas. Benefits include convenience, reduced travel time and costs, and
decreased waiting periods. However, challenges remain, including disparities in
internet access, concerns about data privacy and security, and limitations in performing
physical examinations remotely.
1. What is the main benefit of telemedicine discussed in the passage?
• A. It eliminates the need for all in-person doctor visits
• B. It improves access to healthcare, especially for rural patients
• C. It guarantees lower healthcare costs for everyone
• D. It replaces the need for hospitals
Answer: B
Rationale: The passage highlights that telemedicine "increases access to care for
individuals in rural or underserved areas." While other benefits are mentioned,
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improving access is a central theme. It does not eliminate all in-person visits, guarantee
lower costs, or replace hospitals .
2. Based on information in the passage, what can be inferred about the future of
telemedicine?
• A. It will completely replace traditional in-person healthcare
• B. It will likely remain a viable option alongside traditional care
• C. It will disappear after the pandemic ends
• D. It will only be used for mental health services
Answer: B
Rationale: Given its benefits and rapid expansion during the pandemic, the passage
implies that telemedicine will remain a viable option for healthcare delivery, though
likely alongside traditional care .
3. What does "remote monitoring" most likely refer to in this passage?
• A. Watching patients through a camera without their knowledge
• B. Using technology to track patient health data from a distance
• C. Having patients come to the office for check-ups
• D. Monitoring the internet usage of patients
Answer: B
Rationale: In the context of telemedicine, remote monitoring involves using digital
devices to track patients' vital signs or health data and transmitting that information to
healthcare providers without requiring an in-person visit .
4. The author's tone in this passage can best be described as:
• A. Critical
• B. Informative
• C. Persuasive
• D. Skeptical
Answer: B
Rationale: The passage presents factual information about telemedicine, including
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both benefits and challenges, in a neutral, objective manner. This indicates an
informative tone .
5. Which of the following is NOT mentioned as a challenge of telemedicine?
• A. Disparities in internet access
• B. Concerns about data privacy and security
• C. Limitations in performing remote physical examinations
• D. Higher costs than in-person visits
Answer: D
Rationale: The passage mentions internet access disparities, data privacy/security
concerns, and limitations in remote physical examinations as challenges. Higher costs
are not mentioned .
Passage 2: Antibiotics
The discovery of antibiotics in the early 20th century revolutionized medicine. Penicillin,
discovered by Alexander Fleming in 1928, was the first true antibiotic. It was not until
the 1940s, however, that penicillin was mass-produced and made widely available for
clinical use. Antibiotics work by targeting specific structures or processes in bacterial
cells, such as the cell wall, protein synthesis machinery, or DNA replication. Antibiotics
are classified as bactericidal (killing bacteria) or bacteriostatic (inhibiting bacterial
growth). The overuse and misuse of antibiotics have led to the emergence of antibiotic-
resistant bacteria, a growing global health threat. Nursing responsibilities related to
antibiotics include monitoring for allergic reactions, assessing for therapeutic
effectiveness, and educating patients about completing the full course of treatment
even if symptoms improve.
6. Who discovered penicillin?
• A. Joseph Lister
• B. Louis Pasteur
• C. Alexander Fleming
• D. Edward Jenner
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Answer: C
Rationale: The passage states that penicillin was discovered by Alexander Fleming in
1928 .
7. The word "bactericidal" means:
• A. Inhibiting bacterial growth
• B. Killing bacteria
• C. Preventing infection
• D. Strengthening the immune system
Answer: B
Rationale: The passage defines bactericidal as "killing bacteria," distinguishing it from
bacteriostatic, which inhibits growth .
8. According to the passage, antibiotic resistance is primarily caused by:
• A. The natural aging of bacteria
• B. Overuse and misuse of antibiotics
• C. Patients completing their full course of treatment
• D. The development of vaccines
Answer: B
Rationale: The passage states that "the overuse and misuse of antibiotics have led to
the emergence of antibiotic-resistant bacteria" .
9. Nursing responsibilities related to antibiotics include all of the following EXCEPT:
• A. Monitoring for allergic reactions
• B. Assessing therapeutic effectiveness
• C. Prescribing antibiotics to patients
• D. Educating patients about completing the full course of treatment
Answer: C
Rationale: The passage lists monitoring for allergic reactions, assessing therapeutic
effectiveness, and educating patients as nursing responsibilities. Prescribing antibiotics
is outside the scope of nursing practice .
HESI A2 ENTRANCE ACTUAL EXAM 2026 – 2027
LATEST VERSION QUESTIONS AND ANSWERS
2026 EDITION
HESI A2 Entrance Exam — 250 Practice Questions with Rationales
SECTION 1: READING COMPREHENSION (Questions 1-45)
Passage 1: Telemedicine
Telemedicine refers to the use of digital communication technologies, such as
computers and mobile devices, to provide healthcare services remotely. This practice
allows patients to consult with healthcare providers via video conferencing, secure
messaging, or remote monitoring without needing an in-person office visit.
Telemedicine has expanded rapidly, particularly during the COVID-19 pandemic, as it
reduces exposure risk and increases access to care for individuals in rural or
underserved areas. Benefits include convenience, reduced travel time and costs, and
decreased waiting periods. However, challenges remain, including disparities in
internet access, concerns about data privacy and security, and limitations in performing
physical examinations remotely.
1. What is the main benefit of telemedicine discussed in the passage?
• A. It eliminates the need for all in-person doctor visits
• B. It improves access to healthcare, especially for rural patients
• C. It guarantees lower healthcare costs for everyone
• D. It replaces the need for hospitals
Answer: B
Rationale: The passage highlights that telemedicine "increases access to care for
individuals in rural or underserved areas." While other benefits are mentioned,
, Page 2 of 82
improving access is a central theme. It does not eliminate all in-person visits, guarantee
lower costs, or replace hospitals .
2. Based on information in the passage, what can be inferred about the future of
telemedicine?
• A. It will completely replace traditional in-person healthcare
• B. It will likely remain a viable option alongside traditional care
• C. It will disappear after the pandemic ends
• D. It will only be used for mental health services
Answer: B
Rationale: Given its benefits and rapid expansion during the pandemic, the passage
implies that telemedicine will remain a viable option for healthcare delivery, though
likely alongside traditional care .
3. What does "remote monitoring" most likely refer to in this passage?
• A. Watching patients through a camera without their knowledge
• B. Using technology to track patient health data from a distance
• C. Having patients come to the office for check-ups
• D. Monitoring the internet usage of patients
Answer: B
Rationale: In the context of telemedicine, remote monitoring involves using digital
devices to track patients' vital signs or health data and transmitting that information to
healthcare providers without requiring an in-person visit .
4. The author's tone in this passage can best be described as:
• A. Critical
• B. Informative
• C. Persuasive
• D. Skeptical
Answer: B
Rationale: The passage presents factual information about telemedicine, including
, Page 3 of 82
both benefits and challenges, in a neutral, objective manner. This indicates an
informative tone .
5. Which of the following is NOT mentioned as a challenge of telemedicine?
• A. Disparities in internet access
• B. Concerns about data privacy and security
• C. Limitations in performing remote physical examinations
• D. Higher costs than in-person visits
Answer: D
Rationale: The passage mentions internet access disparities, data privacy/security
concerns, and limitations in remote physical examinations as challenges. Higher costs
are not mentioned .
Passage 2: Antibiotics
The discovery of antibiotics in the early 20th century revolutionized medicine. Penicillin,
discovered by Alexander Fleming in 1928, was the first true antibiotic. It was not until
the 1940s, however, that penicillin was mass-produced and made widely available for
clinical use. Antibiotics work by targeting specific structures or processes in bacterial
cells, such as the cell wall, protein synthesis machinery, or DNA replication. Antibiotics
are classified as bactericidal (killing bacteria) or bacteriostatic (inhibiting bacterial
growth). The overuse and misuse of antibiotics have led to the emergence of antibiotic-
resistant bacteria, a growing global health threat. Nursing responsibilities related to
antibiotics include monitoring for allergic reactions, assessing for therapeutic
effectiveness, and educating patients about completing the full course of treatment
even if symptoms improve.
6. Who discovered penicillin?
• A. Joseph Lister
• B. Louis Pasteur
• C. Alexander Fleming
• D. Edward Jenner
, Page 4 of 82
Answer: C
Rationale: The passage states that penicillin was discovered by Alexander Fleming in
1928 .
7. The word "bactericidal" means:
• A. Inhibiting bacterial growth
• B. Killing bacteria
• C. Preventing infection
• D. Strengthening the immune system
Answer: B
Rationale: The passage defines bactericidal as "killing bacteria," distinguishing it from
bacteriostatic, which inhibits growth .
8. According to the passage, antibiotic resistance is primarily caused by:
• A. The natural aging of bacteria
• B. Overuse and misuse of antibiotics
• C. Patients completing their full course of treatment
• D. The development of vaccines
Answer: B
Rationale: The passage states that "the overuse and misuse of antibiotics have led to
the emergence of antibiotic-resistant bacteria" .
9. Nursing responsibilities related to antibiotics include all of the following EXCEPT:
• A. Monitoring for allergic reactions
• B. Assessing therapeutic effectiveness
• C. Prescribing antibiotics to patients
• D. Educating patients about completing the full course of treatment
Answer: C
Rationale: The passage lists monitoring for allergic reactions, assessing therapeutic
effectiveness, and educating patients as nursing responsibilities. Prescribing antibiotics
is outside the scope of nursing practice .
