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Internal Medicine Board ABIM Exam: 150+ Practice Questions & Verified Answers Comprehensive Study Guide (2026)

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This comprehensive study guide provides a broad review of key concepts relevant to the ABIM Internal Medicine Board Examination, updated for 2026. It includes 150+ practice questions and answer-focused review material covering cardiology, pulmonology, gastroenterology, nephrology, endocrinology, infectious diseases, hematology, oncology, rheumatology, neurology, geriatrics, and general internal medicine. Emphasis is placed on clinical reasoning, differential diagnosis, diagnostic testing, evidence-based management, and application of internal medicine knowledge to board-style clinical scenarios. Claims such as “actual exam,” “100% verified answers,” “graded A+,” and “guaranteed pass” are promotional descriptions and should not be interpreted as official ABIM examination content or guarantees of exam performance.

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INTERNAL MEDICINE BOARD ABIM EXAM 150+
PRACTICE QUESTIONS & VERIFIED ANSWERS
COMPREHENSIVE STUDY GUIDE (2026)
The BP target for patients with stable ischemic heart disease and
hypertension
- answer-130/80

Adults with stage 2 hypertension and an average BP of 20/10 mm Hg
above their BP target
- answer-treat with two first-line drugs of different classes.

The target BP for patients with hypertension and chronic kidney disease
- answer-130/80

Parenteral anticoagulant administration must overlap with warfarin for at
least and until the INR is greater than 2
for
- answer-5d and 24h

Gastrointestinal infections caused by Vibrio species are associated with
ingestion of and can be severe in patients
with dysfunction.
- answer-contaminated seafood, particularly shellfish; liver

HSV-1 Encephalitis radiologic finding
- answer-T2 temporal hyperdensities

Fetal risks associated with SLE mother with anti-Ro/SSA or anti-La/SSB
- answer-Neonatal congenital heart block & neonatal lupus erythematosus

Mycobacterium marinum skin infections
- answer-Papular then ulcerative lesions on upper extremity

Side effects of metoclopramide-stop or reduce?
- answer-Hyperporlactinemia, galactorrhea, tardive dyskenesia; stop

Hormonal therapy for post menopausal women age and
if since
menopause
- answer-<60; <10 years

RTA type II

,Defect:
Location:
Serum K:
Urine pH:
- answer-HCO3
Reabsorption Proximal
Low
High or low

RTA Type I
Defect:
Location:
Serum K:
Urine pH:
- answer-H+
excretion Collecting
Duct
Low
High

RTA Type IV
Defect:
Location:
Serum K:
Urine pH:
- answer-H+& K
excretion Distal
Convoluted Tubule High
Low

AED to avoid in PTSD
- answer-Levetiracetam

Screening for history of colorectal cancer colonoscopy at year
and years after
curative surgical resection; if results of these colonoscopies are normal,
then
years.
- answer-1; 3; 5

PSGN vs. IgA nephropathy
- answer-IgA - 5 days after infx, nl

, C3 PSGN - 10+ days after infx,
low C3
Constrictive pericarditis
treatment 1.
if fails after
(time
) then 2.
- answer-1. Ibuprofen for 2-3 months
2. Pericardiectomy

First-line therapy for localized impetigo.
- answer-topical antibacterial

Treatment of fatigue in multiple sclerosis.
- answer-Modafinil

Asymptomatic gallstones who should get surgery
- answer-High risk for carcinoma: porcelain GB, Stones >3 cm

chronic inflammatory demyelinating polyradiculoneuropathy treatment
- answer-Glucocorticoids $ immunomodulation

Presbycusis
What kind of hearing loss?
Symmetric/Asymmetric?
Frequency lost?
- answer-
Sensorineural
Symmetric
High frequency

The standard treatment regimen for patients with stage I, II, or III anal
squamous cell carcinoma.
- answer-Radiation with 5FU chemo. If fails, surgery

O/P ABx monitoring for renal fxn, CBC, LFTs
- answer-Nafcillin, oxcacillin and carbapenems

O/P ABx monitoring for renal fxn, CBC, NOT LFT
- answer-β-lactam antibiotics excluding nafcillin, oxacillin and carbapenems

O/P ABx monitoring for renal fxn, CBC, and serum K

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Uploaded on
August 13, 2026
Number of pages
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Written in
2026/2027
Type
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